SPYRE THERAPEUTICS INC · CUSIP 00773J202 · CIK 1831942
As of 2026-06-30, Commodore Capital LP reported 846.79K SYRE (shares), valued at $75.18M, or 4.48% of its reported non-derivative portfolio. Filed 2026-08-14.
Verify history & sources →Shares decreased 55.72%; reported value decreased 22.06%, and weight changed -1.10 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds.
Left: % · Right: Shares · Independently scaled axes
Exact data and methodology
Axes scale independently; a crossing does not mean equal values. Weight uses each quarter's total reported non-derivative value. Same CUSIP; missing quarters are gaps, not zero. Revised history may include later disclosures.
| Quarter | Weight | Quantity | Source |
|---|---|---|---|
| Q2 2026 | 4.48% | 846,786 | SEC filing ↗Filed Aug 14, 2026 |
| Q1 2026 | 5.58% | 1,912,380 | SEC filing ↗Filed May 15, 2026 |
| Q4 2025 | 5.21% | 2,388,245 | SEC filing ↗Filed Feb 17, 2026 |
| Q3 2025 | 1.63% | 1,988,084 | SEC filing ↗Filed Nov 14, 2025 |
| Q2 2025 | 2.10% | 1,988,084 | SEC filing ↗Filed Aug 14, 2025 |
| Q1 2025 | 2.36% | 1,988,084 | SEC filing ↗Filed May 15, 2025 |
| Q4 2024 | 3.39% | 1,988,084 | SEC filing ↗Filed Feb 14, 2025 |
| Q3 2024 | 3.65% | 1,988,084 | SEC filing ↗Filed Nov 14, 2024 |
| Q2 2024 | 3.19% | 1,988,084 | SEC filing ↗Filed Aug 14, 2024 |
| Q1 2024 | 4.78% | 1,884,084 | SEC filing ↗Filed May 15, 2024 |
| Q4 2023 | 3.54% | 1,884,084 | SEC filing ↗Filed Feb 14, 2024Amended |
| Q3 2023 | 0.17% | 116,324 | SEC filing ↗Filed Nov 14, 2023 |
History & evidence by quarter
| Quarter | Weight | Quantity | Value | Change explained | Source |
|---|---|---|---|---|---|
| Q3 2023 | 0.17% | 116,324 | $1.42M | The prior quarter is outside the free window. Sign in for the comparison. | SEC filing ↗ Filed Nov 14, 2023 |
| Q4 2023 | 3.54% | 1,884,084 | $40.55M | Shares increased 1519.69%; reported value increased 2745.36%, and weight changed +3.37 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Feb 14, 2024 |
| Q1 2024 | 4.78% | 1,884,084 | $71.46M | Shares unchanged; reported value increased 76.25%, and weight changed +1.24 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed May 15, 2024 |
| Q2 2024 | 3.19% | 1,988,084 | $46.74M | Shares increased 5.52%; reported value decreased 34.60%, and weight changed -1.59 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Aug 14, 2024 |
| Q3 2024 | 3.65% | 1,988,084 | $58.47M | Shares unchanged; reported value increased 25.10%, and weight changed +0.46 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Nov 14, 2024 |
| Q4 2024 | 3.39% | 1,988,084 | $46.28M | Shares unchanged; reported value decreased 20.84%, and weight changed -0.26 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Feb 14, 2025 |
| Q1 2025 | 2.36% | 1,988,084 | $32.08M | Shares unchanged; reported value decreased 30.69%, and weight changed -1.03 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed May 15, 2025 |
| Q2 2025 | 2.10% | 1,988,084 | $29.76M | Shares unchanged; reported value decreased 7.22%, and weight changed -0.26 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Aug 14, 2025 |
| Q3 2025 | 1.63% | 1,988,084 | $33.32M | Shares unchanged; reported value increased 11.96%, and weight changed -0.47 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Nov 14, 2025 |
| Q4 2025 | 5.21% | 2,388,245 | $78.24M | Shares increased 20.13%; reported value increased 134.81%, and weight changed +3.58 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Feb 17, 2026 |
| Q1 2026 | 5.58% | 1,912,380 | $96.46M | Shares decreased 19.93%; reported value increased 23.29%, and weight changed +0.37 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed May 15, 2026 |
| Q2 2026 | 4.48% | 846,786 | $75.18M | Shares decreased 55.72%; reported value decreased 22.06%, and weight changed -1.10 pp. Weight depends on both the security valuation and total portfolio value, not trade proceeds. | SEC filing ↗ Filed Aug 14, 2026 |
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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.