DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 1009258 · Holdings on Sep 30, 2025 · First reported Nov 14, 2025
Top ten holdings
Q3 2025- NUVL23.84%
- CNC4.95%
- MRUS4.40%
- VTRS3.66%
- UTHR2.74%
- RVMD2.61%
- INDV2.58%
- 604749AB72.58%
- NBIX2.55%
- COGT1.99%
Share classes counted separately51.90%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- SPRYWeight decreased · -1.92 pp3.08% → 1.16%Shares -2.22M (-22.84%)
- CNCWeight increased · +1.81 pp3.14% → 4.95%Shares +5.86M (+183.99%)
- COGTWeight increased · +1.65 pp0.34% → 1.99%Shares +6.41M (+242.89%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 29
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | NUVLNUVALENT INC-A View history and evidence | $1.56B | 23.84% | 17.99M shares | 24.91% → 23.84%-1.07 pp 0 (0.00%) | Unchanged | ↗▾ |
| 02 | CNCCENTENE CORP View history and evidence | $322.76M | 4.95% | 9.05M shares | 3.14% → 4.95%+1.81 pp +5.86M (+183.99%) | Added | ↗▾ |
| 03 | MRUSMERUS NV View history and evidence | $286.87M | 4.40% | 3.05M shares | 3.23% → 4.40%+1.17 pp -337.71K (-9.98%) | Reduced | ↗▾ |
| 04 | VTRSVIATRIS INC View history and evidence | $238.58M | 3.66% | 24.10M shares | 3.89% → 3.66%-0.23 pp +75.18K (+0.31%) | Added | ↗▾ |
| 05 | UTHRUNITED THERAPEUTICS CORP View history and evidence | $178.58M | 2.74% | 425.99K shares | 2.82% → 2.74%-0.08 pp -114.63K (-21.20%) | Reduced | ↗▾ |
| 06 | RVMDREVOLUTION MEDICINES INC View history and evidence | $170.47M | 2.61% | 3.65M shares | 2.26% → 2.61%+0.35 pp +266.27K (+7.87%) | Added | ↗▾ |
| 07 | INDVINDIVIOR PLCORD View history and evidence | $168.45M | 2.58% | 6.99M shares | 2.83% → 2.58%-0.25 pp -3.58M (-33.88%) | Reduced | ↗▾ |
| 08 | 604749AB7MIRUM PHARMACEUTICALSNOTE 4.000% 5/0 View history and evidence | $168.19M | 2.58% | 70.00M principal (USD) | 2.25% → 2.58%+0.33 pp 0 (0.00%) | Unchanged | ↗▾ |
| 09 | NBIXNEUROCRINE BIOSCIENCES INC View history and evidence | $166.26M | 2.55% | 1.18M shares | 2.66% → 2.55%-0.11 pp +16.54K (+1.42%) | Added | ↗▾ |
| 10 | COGTCOGENT BIOSCIENCES INC View history and evidence | $130.00M | 1.99% | 9.05M shares | 0.34% → 1.99%+1.65 pp +6.41M (+242.89%) | Added | ↗▾ |
Options overlay 1
$25.83M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
MRNAMODERNA INC View history and evidence | Put | 1.00M | $25.83M | +1.00M | ▾ |
1 / 1 options · preview only
Exited positions 22
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| OSCR OSCAR HEALTH INC - CLASS A | Non-derivative | -11,649,591 | -$249.77M | SEC filing ↗ | SEC filing ↗ |
| 457985AM1 INTEGRA LIFESCIENCES HLD | Non-derivative | -174,364,000 | -$172.86M | SEC filing ↗ | SEC filing ↗ |
| 02043QAB3 ALNYLAM PHARMACEUTICALS | Non-derivative | -110,000,000 | -$143.17M | SEC filing ↗ | SEC filing ↗ |
3 / 22 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1009258 · Period 2025-09-30
Data loaded 2026-09-23 · First reported 2025-11-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 6550740151
}Research all 152 reported holdings.
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