ARCH Venture Management, LLC
CIK 1274403 · Holdings on Jun 30, 2026 · First reported Aug 14, 2026
Top ten holdings
Q2 2026- PBLS15.95%
- BEAM14.16%
- RAPP14.12%
- SPTX12.42%
- ERAS11.81%
- VIR11.76%
- MAZE11.18%
- LYEL4.14%
- GENB2.98%
- TXG0.76%
Share classes counted separately99.28%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- MAZEWeight decreased · -6.98 pp18.16% → 11.18%Shares 0 (0.00%)
- LYELWeight decreased · -5.48 pp9.62% → 4.14%Shares 0 (0.00%)
- VIRWeight decreased · -5.33 pp17.09% → 11.76%Shares -222.50K (-1.72%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 12
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | PBLSPARABILIS MEDICINES INC View history and evidence | $175.52M | 15.95% | 6.41M shares | Prior unavailable +6.41M | New | ↗▾ |
| 02 | BEAMBEAM THERAPEUTICS INC View history and evidence | $155.77M | 14.16% | 4.54M shares | 15.98% → 14.16%-1.82 pp 0 (0.00%) | Unchanged | ↗▾ |
| 03 | RAPPRAPPORT THERAPEUTICS INC View history and evidence | $155.38M | 14.12% | 3.73M shares | 17.23% → 14.12%-3.11 pp 0 (0.00%) | Unchanged | ↗▾ |
| 04 | SPTXSEAPORT THERAPEUTICS INCCOMMON STOCK View history and evidence | $136.60M | 12.42% | 6.29M shares | Prior unavailable +6.29M | New | ↗▾ |
| 05 | ERASERASCA INC View history and evidence | $129.92M | 11.81% | 7.09M shares | 16.95% → 11.81%-5.14 pp 0 (0.00%) | Unchanged | ↗▾ |
| 06 | VIRVIR BIOTECHNOLOGY INC View history and evidence | $129.35M | 11.76% | 12.69M shares | 17.09% → 11.76%-5.33 pp -222.50K (-1.72%) | Reduced | ↗▾ |
| 07 | MAZEMAZE THERAPEUTICS INC View history and evidence | $122.98M | 11.18% | 4.12M shares | 18.16% → 11.18%-6.98 pp 0 (0.00%) | Unchanged | ↗▾ |
| 08 | LYELLYELL IMMUNOPHARMA INCCOM NEW View history and evidence | $45.53M | 4.14% | 3.25M shares | 9.62% → 4.14%-5.48 pp 0 (0.00%) | Unchanged | ↗▾ |
| 09 | GENBGENERATE BIOMEDICINES INCCOM SHS View history and evidence | $32.80M | 2.98% | 1.94M shares | 3.59% → 2.98%-0.61 pp 0 (0.00%) | Unchanged | ↗▾ |
| 10 | TXG10X GENOMICS INC-CLASS ACL A COM View history and evidence | $8.35M | 0.76% | 217.83K shares | 0.68% → 0.76%+0.08 pp 0 (0.00%) | Unchanged | ↗▾ |
Options overlay 0
No options reported this quarter.
Exited positions 1
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| QTTB Q32 BIO INC | Non-derivative | -320,482 | -$2.06M | SEC filing ↗ | SEC filing ↗ |
1 / 1 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1274403 · Period Jun 30, 2026
Data loaded Sep 23, 2026 · First reported Aug 14, 2026
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 1100261770
}Take these holdings further.
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