RA CAPITAL MANAGEMENT, L.P.
CIK 1346824 · Holdings on Dec 31, 2024 · First reported Feb 14, 2025
Top ten holdings
Q4 2024- ASND18.53%
- PCVX9.47%
- JANX7.39%
- RYTM4.53%
- LEGN3.25%
- EWTX3.17%
- NAMS3.03%
- 9666679D3.00%
- ACLX2.84%
- RNA2.44%
Share classes counted separately57.65%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- JANXWeight increased · +2.59 pp4.80% → 7.39%Shares +1.20M (+13.09%)
- PCVXWeight decreased · -1.98 pp11.45% → 9.47%Shares 0 (0.00%)
- ASNDWeight increased · +1.81 pp16.72% → 18.53%Shares +402.32K (+4.14%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 30
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | ASNDASCENDIS PHARMA A/SSH View history and evidence | $1.39B | 18.53% | 10.11M shares | 16.72% → 18.53%+1.81 pp +402.32K (+4.14%) | Added | ↗▾ |
| 02 | PCVXVAXCYTE INCSH View history and evidence | $711.30M | 9.47% | 8.69M shares | 11.45% → 9.47%-1.98 pp 0 (0.00%) | Unchanged | ↗▾ |
| 03 | JANXJANUX THERAPEUTICS INCSH View history and evidence | $554.98M | 7.39% | 10.37M shares | 4.80% → 7.39%+2.59 pp +1.20M (+13.09%) | Added | ↗▾ |
| 04 | RYTMRHYTHM PHARMACEUTICALS INCSH View history and evidence | $340.61M | 4.53% | 6.08M shares | 3.68% → 4.53%+0.85 pp 0 (0.00%) | Unchanged | ↗▾ |
| 05 | LEGNLEGEND BIOTECH CORP-ADRSH View history and evidence | $244.28M | 3.25% | 7.51M shares | 4.22% → 3.25%-0.97 pp 0 (0.00%) | Unchanged | ↗▾ |
| 06 | EWTXEDGEWISE THERAPEUTICS INCSH View history and evidence | $237.87M | 3.17% | 8.91M shares | 2.74% → 3.17%+0.43 pp 0 (0.00%) | Unchanged | ↗▾ |
| 07 | NAMSNEWAMSTERDAM PHARMA CO NVSH View history and evidence | $227.32M | 3.03% | 8.85M shares | 1.54% → 3.03%+1.49 pp +781.00K (+9.69%) | Added | ↗▾ |
| 08 | 9666679DWAVE LIFE SCIENCES LTDSH View history and evidence | $225.16M | 3.00% | 18.20M shares | 1.72% → 3.00%+1.28 pp 0 (0.00%) | Unchanged | ↗▾ |
| 09 | ACLXARCELLX INCSH View history and evidence | $213.76M | 2.84% | 2.79M shares | 1.78% → 2.84%+1.06 pp +935.85K (+50.55%) | Added | ↗▾ |
| 10 | RNAAVIDITY BIOSCIENCES INCSH View history and evidence | $183.22M | 2.44% | 6.30M shares | 3.34% → 2.44%-0.90 pp 0 (0.00%) | Unchanged | ↗▾ |
Options overlay 0
No options reported this quarter.
Exited positions 9
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| BIIB BIOGEN INC | Non-derivative | -1,184,456 | -$229.59M | SEC filing ↗ | SEC filing ↗ |
| CGON CG ONCOLOGY INC | Non-derivative | -1,397,433 | -$52.73M | SEC filing ↗ | SEC filing ↗ |
| ANRO ALTO NEUROSCIENCE INC | Non-derivative | -2,075,154 | -$23.74M | SEC filing ↗ | SEC filing ↗ |
3 / 9 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1346824 · Period 2024-12-31
Data loaded 2026-09-23 · First reported 2025-02-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 7514204405
}Research all 89 reported holdings.
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