SPHERA FUNDS MANAGEMENT LTD.
CIK 1496201 · Holdings on Jun 30, 2026 · First reported Aug 14, 2026
Top ten holdings
Q2 2026- TEVAN7.27%
- MLYS5.68%
- TSEM4.04%
- SNDX3.17%
- BIIB2.99%
- RARE2.81%
- BMRN2.69%
- CYTK2.68%
- BBIO2.61%
- COGT2.54%
Share classes counted separately36.48%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- CYTKWeight increased · +2.23 pp0.45% → 2.68%Shares +180.17K (+452.50%)
- NVMIWeight decreased · -2.03 pp3.99% → 1.96%Shares -28.20K (-52.84%)
- TEVANWeight increased · +1.38 pp5.89% → 7.27%Shares +363.11K (+31.94%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 25
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | TEVANTEVA PHARMACEUTICAL-SP ADRSPONSORED ADS View history and evidence | $50.82M | 7.27% | 1.50M shares | 5.89% → 7.27%+1.38 pp +363.11K (+31.94%) | Added | ▾ |
| 02 | MLYSMINERALYS THERAPEUTICS INC View history and evidence | $39.66M | 5.68% | 1.47M shares | 6.24% → 5.68%-0.56 pp +130.00K (+9.70%) | Added | ▾ |
| 03 | TSEMTOWER SEMICONDUCTOR LTDSHS NEW View history and evidence | $28.22M | 4.04% | 108.27K shares | 4.40% → 4.04%-0.36 pp -37.47K (-25.71%) | Reduced | ▾ |
| 04 | SNDXSYNDAX PHARMACEUTICALS INC View history and evidence | $22.18M | 3.17% | 1.01M shares | 2.91% → 3.17%+0.26 pp +290.04K (+40.03%) | Added | ▾ |
| 05 | BIIBBIOGEN INC View history and evidence | $20.88M | 2.99% | 96.63K shares | 2.92% → 2.99%+0.07 pp +4.10K (+4.43%) | Added | ▾ |
| 06 | RAREULTRAGENYX PHARMACEUTICAL IN View history and evidence | $19.65M | 2.81% | 588.49K shares | 2.92% → 2.81%-0.11 pp -220.84K (-27.29%) | Reduced | ▾ |
| 07 | BMRNBIOMARIN PHARMACEUTICAL INC View history and evidence | $18.80M | 2.69% | 328.55K shares | 1.36% → 2.69%+1.33 pp +188.65K (+134.85%) | Added | ▾ |
| 08 | CYTKCYTOKINETICS INCCOM NEW View history and evidence | $18.74M | 2.68% | 219.99K shares | 0.45% → 2.68%+2.23 pp +180.17K (+452.50%) | Added | ▾ |
| 09 | BBIOBRIDGEBIO PHARMA INC View history and evidence | $18.27M | 2.61% | 245.35K shares | 3.13% → 2.61%-0.52 pp +100 (+0.04%) | Added | ▾ |
| 10 | COGTCOGENT BIOSCIENCES INC View history and evidence | $17.78M | 2.54% | 459.34K shares | 2.76% → 2.54%-0.22 pp +43.00K (+10.33%) | Added | ▾ |
Options overlay 8
$67.71M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
XBISS SPDR S&P BIOTECH ETFST STR SP BIOT View history and evidence | Put | 150.00K | $23.74M | -50.00K (-25.00%) | ▾ |
BIIBBIOGEN INC View history and evidence | Call | 100.00K | $21.61M | +100.00K | ▾ |
CYTKCYTOKINETICS INCCOM NEW View history and evidence | Call | 100.00K | $8.52M | -159.30K (-61.43%) | ▾ |
3 / 8 options · preview only
Exited positions 18
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| 03152W109 AMICUS THERAPEUTICS INC | Non-derivative | -603,377 | -$8.72M | SEC filing ↗ | SEC filing ↗ |
| CLBT CELLEBRITE DI LTD | Non-derivative | -631,521 | -$8.70M | SEC filing ↗ | SEC filing ↗ |
| APLS APELLIS PHARMACEUTICALS INC | Non-derivative | -214,914 | -$8.65M | SEC filing ↗ | SEC filing ↗ |
3 / 18 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1496201 · Period 2026-06-30
Data loaded 2026-09-23 · First reported 2026-08-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 766539858
}Research all 105 reported holdings.
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