Ikarian Capital, LLC
CIK 1778253 · Holdings on Dec 31, 2024 · First reported Feb 14, 2025
Top ten holdings
Q4 2024- TARS9.61%
- CRNX7.54%
- SRRK4.41%
- BPMC4.22%
- FBRX3.95%
- VRDN2.57%
- ELVN2.53%
- TGTX2.50%
- INSM2.36%
- GPCR2.20%
Share classes counted separately41.89%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- RCUSWeight decreased · -1.92 pp3.53% → 1.61%Shares -365.64K (-49.14%)
- BPMCWeight increased · +1.78 pp2.44% → 4.22%Shares +84.37K (+99.26%)
- ELVNWeight decreased · -1.43 pp3.96% → 2.53%Shares -105.03K (-21.02%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 25
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | TARSTARSUS PHARMACEUTICALS INC View history and evidence | $33.65M | 9.61% | 607.69K shares | 10.52% → 9.61%-0.91 pp -422.59K (-41.02%) | Reduced | ↗▾ |
| 02 | CRNXCRINETICS PHARMACEUTICALS IN View history and evidence | $26.41M | 7.54% | 516.43K shares | 6.77% → 7.54%+0.77 pp +89.52K (+20.97%) | Added | ↗▾ |
| 03 | SRRKSCHOLAR ROCK HOLDING CORP View history and evidence | $15.44M | 4.41% | 357.19K shares | Prior unavailable +357.19K | New | ↗▾ |
| 04 | BPMCBLUEPRINT MEDICINES CORP View history and evidence | $14.77M | 4.22% | 169.37K shares | 2.44% → 4.22%+1.78 pp +84.37K (+99.26%) | Added | ↗▾ |
| 05 | FBRXFORTE BIOSCIENCES INCCOM NEW View history and evidence | $13.84M | 3.95% | 609.23K shares | Prior unavailable +609.23K | New | ↗▾ |
| 06 | VRDNVIRIDIAN THERAPEUTICS INC View history and evidence | $9.01M | 2.57% | 469.95K shares | 3.53% → 2.57%-0.96 pp -30.03K (-6.01%) | Reduced | ↗▾ |
| 07 | ELVNENLIVEN THERAPEUTICS INC View history and evidence | $8.88M | 2.53% | 394.54K shares | 3.96% → 2.53%-1.43 pp -105.03K (-21.02%) | Reduced | ↗▾ |
| 08 | TGTXTG THERAPEUTICS INC View history and evidence | $8.77M | 2.50% | 291.24K shares | Prior unavailable +291.24K | New | ↗▾ |
| 09 | INSMINSMED INCCOM PAR $.01 View history and evidence | $8.27M | 2.36% | 119.80K shares | 3.51% → 2.36%-1.15 pp -35.03K (-22.63%) | Reduced | ↗▾ |
| 10 | GPCRSTRUCTURE THERAPEUTICS INCSPONSORED ADS View history and evidence | $7.70M | 2.20% | 284.08K shares | 1.57% → 2.20%+0.63 pp +168.88K (+146.60%) | Added | ↗▾ |
Options overlay 49
$385.06M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
XBISS SPDR S&P BIOTECH ETFS&P BIOTECH View history and evidence | Put | 750.00K | $67.55M | +250.00K (+50.00%) | ▾ |
XBISS SPDR S&P BIOTECH ETFS&P BIOTECH View history and evidence | Call | 700.00K | $63.04M | +700.00K | ▾ |
TSNTYSON FOODS INC-CL ACL A View history and evidence | Put | 630.00K | $36.19M | +630.00K | ▾ |
3 / 49 options · preview only
Exited positions 43
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| VRTX VERTEX PHARMACEUTICALS INC | Put | -100,000 | -$46.51M | SEC filing ↗ | SEC filing ↗ |
| VRTX VERTEX PHARMACEUTICALS INC | Call | -100,000 | -$46.51M | SEC filing ↗ | SEC filing ↗ |
| JANX JANUX THERAPEUTICS INC | Put | -365,200 | -$16.59M | SEC filing ↗ | SEC filing ↗ |
3 / 43 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1778253 · Period 2024-12-31
Data loaded 2026-09-23 · First reported 2025-02-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 735256871
}Research all 171 reported holdings.
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