Company · Ownership research

Definium Therapeutics, Inc. DFTX

CIK 0001813814 · CUSIP 24477V105

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 24477V105 (DFTX), not CUSIP 24477V905 (DFTX), CUSIP 24477V955 (DFTX), CUSIP 60255C905 (DFTX), CUSIP 60255C955 (DFTX), and does not merge CUSIPs.

This page lists the top 20 of 246 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	BlackRock, Inc. CIK 2012383 · View history	$160.28M 8,480,230 shares	0.00%	+8.48MNew	SEC filing ↗ May 13, 2026	▾
02	Driehaus Capital Management LLC CIK 938206 · View history	$111.73M 5,911,889 shares	0.82%	-625.31K(-9.60%)Reduced	SEC filing ↗ May 15, 2026	▾
03	Avoro Capital Advisors LLC CIK 1633313 · View history	$94.50M 5,000,000 shares	0.93%	+5.00MNew	SEC filing ↗ May 15, 2026	▾
04	JANUS HENDERSON GROUP PLC CIK 1274173 · Amended · View history	$67.23M 3,556,041 shares	0.03%	+3.56MNew	SEC filing ↗ May 18, 2026	▾
05	Deep Track Capital, LP CIK 1856083 · View history	$56.70M 3,000,000 shares	1.17%	+3.00MNew	SEC filing ↗ May 15, 2026	▾
06	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$47.17M 2,495,399 shares	0.00%	+2.50MNew	SEC filing ↗ May 15, 2026	▾
07	STATE STREET CORP CIK 93751 · View history	$46.72M 2,471,873 shares	0.00%	+2.47MNew	SEC filing ↗ May 15, 2026	▾
08	Octagon Capital Advisors LP CIK 1839435 · View history	$46.12M 2,440,000 shares	5.10%	+2.44MNew	SEC filing ↗ May 15, 2026	▾
09	COMMODORE CAPITAL LP CIK 1831942 · View history	$37.80M 2,000,000 shares	2.19%	+2.00MNew	SEC filing ↗ May 15, 2026	▾
10	FMR LLC CIK 315066 · View history	$34.20M 1,809,610 shares	0.00%	+1.81MNew	SEC filing ↗ May 15, 2026	▾
11	Trails Edge Capital Partners, LP CIK 2077247 · View history	$32.85M 1,738,110 shares	7.73%	+1.74MNew	SEC filing ↗ May 15, 2026	▾
12	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$31.67M 1,675,411 shares	0.00%	+1.68MNew	SEC filing ↗ May 15, 2026	▾
13	ArrowMark Colorado Holdings LLC CIK 1483859 · View history	$30.14M 1,594,717 shares	0.80%	+1.59MNew	SEC filing ↗ May 15, 2026	▾
14	CITADEL ADVISORS LLC CIK 1423053 · View history	$25.20M 1,333,442 shares	0.02%	+1.33MNew	SEC filing ↗ May 15, 2026	▾
15	WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history	$24.66M 1,304,749 shares	0.00%	+1.30MNew	SEC filing ↗ May 15, 2026	▾
16	Candriam S.C.A. CIK 1537014 · View history	$24.45M 1,293,629 shares	0.13%	+1.29MNew	SEC filing ↗ Apr 30, 2026	▾
17	Balyasny Asset Management L.P. CIK 1218710 · View history	$24.08M 1,274,221 shares	0.05%	+1.27MNew	SEC filing ↗ May 15, 2026	▾
18	TWO SIGMA INVESTMENTS, LP CIK 1179392 · View history	$22.71M 1,201,610 shares	0.02%	+1.20MNew	SEC filing ↗ May 15, 2026	▾
19	MARSHALL WACE, LLP CIK 1318757 · View history	$22.70M 1,200,825 shares	0.02%	-1.77M(-59.60%)Reduced	SEC filing ↗ May 15, 2026	▾
20	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$21.73M 1,150,000 shares	0.03%	+1.15MNew	SEC filing ↗ May 15, 2026	▾

Showing 20 / 246 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

246

Cancelled or null records excluded

Disclosed shares

78,037,597

Not deduplicated across managers

Disclosed value

$1.47B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Definium Therapeutics, Inc. · Q1 2026

Explore all 246 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.