Company · Ownership research

Denali Therapeutics Inc. DNLI

CIK 0001714899 · CUSIP 24823R105

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 24823R105 (DNLI), not CUSIP 24823R905 (DNLI), CUSIP 24823R955 (DNLI), and does not merge CUSIPs.

This page lists the top 20 of 205 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	BAILLIE GIFFORD & CO CIK 1088875 · View history	$319.59M 13,763,596 shares	0.25%	-277.63K(-2.00%)Reduced	SEC filing ↗ Jul 25, 2024	▾
02	BlackRock Inc. CIK 1364742 · View history	$305.91M 13,174,562 shares	0.01%	+974.71K(+8.00%)Added	SEC filing ↗ Aug 13, 2024	▾
03	VANGUARD GROUP INC CIK 102909 · View history	$262.67M 11,312,439 shares	0.01%	+344.15K(+3.10%)Added	SEC filing ↗ Aug 13, 2024	▾
04	WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history	$228.11M 9,823,767 shares	0.04%	+1.55M(+18.80%)Added	SEC filing ↗ Aug 14, 2024	▾
05	Capital Research Global Investors CIK 1422848 · View history	$165.48M 7,126,533 shares	0.04%	+1.08M(+17.80%)Added	SEC filing ↗ Aug 13, 2024	▾
06	Temasek Holdings (Private) Ltd CIK 1021944 · Amended · View history	$132.50M 5,706,345 shares	0.62%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2024	▾
07	Crestline Management, LP CIK 1536054 · View history	$110.54M 4,760,732 shares	8.67%	-450.00K(-8.60%)Reduced	SEC filing ↗ Aug 14, 2024	▾
08	STATE STREET CORP CIK 93751 · View history	$102.98M 4,434,790 shares	0.00%	-1.89M(-29.90%)Reduced	SEC filing ↗ Aug 14, 2024	▾
09	TAKEDA PHARMACEUTICAL CO LTD CIK 1395064 · View history	$97.86M 4,214,559 shares	42.13%	0(0.00%)Unchanged	SEC filing ↗ Feb 13, 2025	▾
10	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$86.65M 3,731,695 shares	1.11%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2024	▾
11	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$69.27M 2,982,538 shares	0.01%	+222.91K(+8.10%)Added	SEC filing ↗ Aug 9, 2024	▾
12	MARSHALL WACE, LLP CIK 1318757 · View history	$56.17M 2,418,833 shares	0.08%	+272.45K(+12.70%)Added	SEC filing ↗ Aug 14, 2024	▾
13	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC CIK 861177 · View history	$53.35M 2,297,716 shares	0.02%	+1.61M(+234.30%)Added	SEC filing ↗ Aug 14, 2024	▾
14	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$52.37M 2,255,470 shares	0.01%	+661.14K(+41.50%)Added	SEC filing ↗ Aug 14, 2024	▾
15	ALLIANCEBERNSTEIN L.P. CIK 1109448 · View history	$46.87M 2,018,534 shares	0.02%	+1.88M(+1,366.70%)Added	SEC filing ↗ Aug 14, 2024	▾
16	Camber Capital Management LP CIK 1444043 · View history	$46.44M 2,000,000 shares	1.79%	+500.00K(+33.30%)Added	SEC filing ↗ Aug 14, 2024	▾
17	Bank of New York Mellon Corp CIK 1390777 · View history	$35.77M 1,540,271 shares	0.01%	-237.64K(-13.40%)Reduced	SEC filing ↗ Jul 25, 2024	▾
18	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$32.91M 1,417,472 shares	0.01%	+84.52K(+6.30%)Added	SEC filing ↗ Aug 9, 2024	▾
19	Casdin Capital, LLC CIK 1534261 · Amended · View history	$30.19M 1,300,000 shares	2.30%	0(0.00%)Unchanged	SEC filing ↗ Oct 18, 2024	▾
20	MORGAN STANLEY CIK 895421 · Amended · View history	$28.42M 1,223,878 shares	0.00%	+295.75K(+31.90%)Added	SEC filing ↗ May 14, 2025	▾

Showing 20 / 205 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

205

Cancelled or null records excluded

Disclosed shares

123,900,358

Not deduplicated across managers

Disclosed value

$2.88B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Denali Therapeutics Inc. · Q2 2024

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.