Structure Therapeutics Inc. GPCR
CIK 0001888886 · CUSIP 86366E106
Quarter-end disclosures, not live holdings.
Top 20 institutions
Weight means this stock's share of the manager's own portfolio.
| # | Manager | Value | Manager weight | Change vs prior | Source | |
|---|---|---|---|---|---|---|
| 01 | FMR LLC CIK 315066 · View history | $605.94M 8,712,251 shares | 0.03% | +3.46M(+65.9%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 02 | WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history | $495.33M 7,121,984 shares | 0.09% | +1.43M(+25.2%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 03 | Avoro Capital Advisors LLC CIK 1633313 · Amended · View history | $455.94M 6,555,555 shares | 4.48% | +1.40M(+27.2%)Added | SEC filing ↗ Mar 16, 2026 | ▾ |
| 04 | JANUS HENDERSON GROUP PLC CIK 1274173 · View history | $354.01M 5,090,148 shares | 0.16% | +641.32K(+14.4%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 05 | Deep Track Capital, LP CIK 1856083 · View history | $285.97M 4,111,782 shares | 6.52% | -104.03K(-2.5%)Reduced | SEC filing ↗ Feb 13, 2026 | ▾ |
| 06 | BVF INC/IL CIK 1056807 · View history | $241.97M 3,479,022 shares | 8.15% | +275.11K(+8.6%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 07 | MORGAN STANLEY CIK 895421 · Amended · View history | $145.21M 2,087,834 shares | 0.01% | +1.51M(+261.4%)Added | SEC filing ↗ May 27, 2026 | ▾ |
| 08 | PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history | $116.23M 1,671,138 shares | 0.01% | +1.38M(+477.5%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 09 | Driehaus Capital Management LLC CIK 938206 · View history | $114.23M 1,642,444 shares | 0.78% | +768.94K(+88.0%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 10 | BAKER BROS. ADVISORS LP CIK 1263508 · View history | $99.63M 1,432,529 shares | 0.58% | -123.58K(-7.9%)Reduced | SEC filing ↗ Feb 17, 2026 | ▾ |
| 11 | PRINCIPAL FINANCIAL GROUP INC CIK 1126328 · View history | $89.32M 1,284,210 shares | 0.05% | +496.73K(+63.1%)Added | SEC filing ↗ Feb 2, 2026 | ▾ |
| 12 | Casdin Capital, LLC CIK 1534261 · View history | $81.72M 1,175,000 shares | 5.08% | -380.00K(-24.4%)Reduced | SEC filing ↗ Feb 17, 2026 | ▾ |
| 13 | ORBIMED ADVISORS LLC CIK 1055951 · View history | $80.80M 1,161,803 shares | 1.66% | +22.50K(+2.0%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 14 | Siren, L.L.C. CIK 2005245 · View history | $75.02M 1,078,698 shares | 2.24% | +51.89K(+5.1%)Added | SEC filing ↗ Feb 13, 2026 | ▾ |
| 15 | TCG Crossover Management, LLC CIK 1839948 · View history | $64.05M 920,857 shares | 2.12% | -142.14K(-13.4%)Reduced | SEC filing ↗ Feb 17, 2026 | ▾ |
| 16 | CAPITOLIS LIQUID GLOBAL MARKETS LLC CIK 2094379 · View history | $61.09M 878,300 shares | 0.36% | +878.30KNew | SEC filing ↗ Feb 17, 2026 | ▾ |
| 17 | FRANKLIN RESOURCES INC CIK 38777 · View history | $60.55M 870,582 shares | 0.01% | +124.85K(+16.7%)Added | SEC filing ↗ Feb 11, 2026 | ▾ |
| 18 | ALLIANCEBERNSTEIN L.P. CIK 1109448 · View history | $59.04M 848,851 shares | 0.02% | +819.29K(+2771.7%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
| 19 | DEUTSCHE BANK AG\ CIK 948046 · View history | $58.50M 841,162 shares | 0.02% | +841.16KNew | SEC filing ↗ Feb 11, 2026 | ▾ |
| 20 | CITADEL ADVISORS LLC CIK 1423053 · View history | $53.73M 772,518 shares | 0.04% | +328.72K(+74.1%)Added | SEC filing ↗ Feb 17, 2026 | ▾ |
Showing 20 / 197 institutions. The complete set is available through the API.
Coverage & totals by quarter
Reporting institutions by quarter
Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.
Explore all 197 reporting institutions.
This page includes 20 of 197 reporting institutions. Sign in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.
- Download CSV
- Earlier quarters
- Advanced screening & filtering
- API & AI access
+ New accounts get free API credits to explore data beyond ownership filings.
For AI agents & developers
The initial HTML of this page carries its exact data as script#research-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 20 of 197 reporting institutions; totals use the complete disclosed data.
Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP.
MCP https://api.akkrudata.ai/mcp
get_institutional_security_holders
{"cusip":"86366E106","quarter":"2025Q4","type":"positions","page_size":100}Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.
- MCP endpoint
- https://api.akkrudata.ai/mcp
- API / MCP documentation
- /documents
- llms.txt
- /llms.txt
Sources, coverage & how to read this data
Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.