Company · Ownership research

Milestone Pharmaceuticals Inc. MIST

CIK 0001408443 · CUSIP 59935V107

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 59935V107 (MIST), not CUSIP 59935V907 (MIST), CUSIP 59935V957 (MIST), and does not merge CUSIPs.

This page lists the top 20 of 61 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$13.95M 6,976,000 shares	0.02%	+6.98MNew	SEC filing ↗ Nov 14, 2025	▾
02	Propel Bio Management, LLC CIK 1969764 · View history	$10.25M 5,124,890 shares	10.26%	+3.33M(+186.10%)Added	SEC filing ↗ Nov 12, 2025	▾
03	ORBIMED ADVISORS LLC CIK 1055951 · View history	$6.44M 3,221,828 shares	0.15%	+3.22MNew	SEC filing ↗ Nov 14, 2025	▾
04	MORGAN STANLEY CIK 895421 · Amended · View history	$5.94M 2,969,067 shares	0.00%	+2.15M(+261.90%)Added	SEC filing ↗ May 27, 2026	▾
05	Simplify Asset Management Inc. CIK 1846368 · View history	$5.67M 2,832,974 shares	0.11%	+1.84M(+186.20%)Added	SEC filing ↗ Oct 20, 2025	▾
06	RTW INVESTMENTS, LP CIK 1493215 · View history	$5.01M 2,506,102 shares	0.06%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
07	Pathstone Holdings, LLC CIK 2011612 · View history	$2.00M 1,000,000 shares	0.01%	+1.00MNew	SEC filing ↗ Nov 13, 2025	▾
08	SPHERA FUNDS MANAGEMENT LTD. CIK 1496201 · View history	$1.64M 820,000 shares	0.39%	+820.00KNew	SEC filing ↗ Nov 14, 2025	▾
09	TORONTO DOMINION BANK CIK 947263 · View history	$1.50M 750,000 shares	0.00%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
10	Boxer Capital Management, LLC CIK 2018299 · Amended · View history	$1.33M 666,666 shares	0.42%	+666.67KNew	SEC filing ↗ Nov 14, 2025	▾
11	Affinity Asset Advisors, LLC CIK 1773195 · View history	$1.33M 666,666 shares	0.12%	+666.67KNew	SEC filing ↗ Nov 13, 2025	▾
12	TWO SIGMA INVESTMENTS, LP CIK 1179392 · View history	$1.33M 666,551 shares	0.00%	+666.55KNew	SEC filing ↗ Nov 14, 2025	▾
13	Lion Point Capital, LP CIK 1643354 · View history	$1.32M 658,553 shares	7.48%	+109.75K(+20.00%)Added	SEC filing ↗ Nov 14, 2025	▾
14	CITADEL ADVISORS LLC CIK 1423053 · View history	$1.02M 512,067 shares	0.00%	+512.07KNew	SEC filing ↗ Nov 14, 2025	▾
15	MARSHALL WACE, LLP CIK 1318757 · View history	$850.06K 425,028 shares	0.00%	+425.03KNew	SEC filing ↗ Nov 13, 2025	▾
16	JANE STREET GROUP, LLC CIK 1595888 · View history	$816.98K 408,492 shares	0.00%	+376.56K(+1,179.20%)Added	SEC filing ↗ Nov 14, 2025	▾
17	MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history	$803.12K 401,559 shares	0.00%	+401.56KNew	SEC filing ↗ Nov 14, 2025	▾
18	UBS Group AG CIK 1610520 · View history	$795.07K 397,534 shares	0.00%	+74.89K(+23.20%)Added	SEC filing ↗ Nov 13, 2025	▾
19	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$713.13K 356,567 shares	0.00%	+237.12K(+198.50%)Added	SEC filing ↗ Nov 14, 2025	▾
20	SUSQUEHANNA INTERNATIONAL GROUP, LLP CIK 1446194 · View history	$513.54K 256,772 shares	0.00%	+193.40K(+305.20%)Added	SEC filing ↗ Nov 14, 2025	▾

Showing 20 / 61 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

34,138,461

Not deduplicated across managers

Disclosed value

$68.28M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Milestone Pharmaceuticals Inc. · Q3 2025

Explore all 61 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.