Company · Ownership research

Silence Therapeutics plc SLN

CIK 0001479615 · CUSIP 82686Q101

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

This page lists the top 20 of 56 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	TCG Crossover Management, LLC CIK 1839948 · View history	$17.59M 3,033,560 shares	2.01%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
02	Siren, L.L.C. CIK 2005245 · View history	$16.89M 2,911,438 shares	0.87%	+121.61K(+4.40%)Added	SEC filing ↗ Aug 13, 2025	▾
03	Redmile Group, LLC CIK 1425738 · View history	$12.56M 2,164,777 shares	1.34%	-50.17K(-2.30%)Reduced	SEC filing ↗ Aug 14, 2025	▾
04	Lombard Odier Asset Management (USA) Corp CIK 1491719 · View history	$7.81M 1,849,734 shares	1.96%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
05	MORGAN STANLEY CIK 895421 · View history	$7.03M 1,211,758 shares	0.00%	-788.35K(-39.40%)Reduced	SEC filing ↗ Aug 14, 2025	▾
06	Vivo Capital, LLC CIK 1674712 · View history	$6.41M 1,105,454 shares	0.66%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
07	Nantahala Capital Management, LLC CIK 1472322 · View history	$6.05M 1,042,427 shares	0.43%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
08	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$5.63M 970,130 shares	0.23%	-178.46K(-15.50%)Reduced	SEC filing ↗ Aug 14, 2025	▾
09	Nextech Invest, Ltd. CIK 1595430 · View history	$5.52M 952,400 shares	1.05%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
10	CANTOR FITZGERALD, L. P. CIK 1024896 · View history	$4.58M 789,039 shares	0.11%	+15.19K(+2.00%)Added	SEC filing ↗ Aug 14, 2025	▾
11	5AM Venture Management, LLC CIK 1799883 · View history	$2.76M 476,200 shares	1.06%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
12	SG Americas Securities, LLC CIK 1313360 · View history	$1.79M 308,331 shares	0.01%	+42(0.00%)Added	SEC filing ↗ Aug 8, 2025	▾
13	BOOTHBAY FUND MANAGEMENT, LLC CIK 1549230 · View history	$1.46M 252,421 shares	0.04%	+2.41K(+1.00%)Added	SEC filing ↗ Aug 14, 2025	▾
14	Ikarian Capital, LLC CIK 1778253 · View history	$1.40M 873,568 shares	0.46%	+873.57KNew	SEC filing ↗ Aug 14, 2025	▾
15	UBS Group AG CIK 1610520 · View history	$1.33M 228,509 shares	0.00%	-91.00K(-28.50%)Reduced	SEC filing ↗ Aug 14, 2025	▾
16	MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history	$1.15M 198,647 shares	0.00%	-198.22K(-49.90%)Reduced	SEC filing ↗ Aug 14, 2025	▾
17	M28 Capital Management LP CIK 1807489 · View history	$1.07M 185,100 shares	1.83%	0(0.00%)Unchanged	SEC filing ↗ Aug 13, 2025	▾
18	HSBC HOLDINGS PLC CIK 873630 · View history	$1.02M 172,834 shares	0.00%	0(0.00%)Unchanged	SEC filing ↗ Aug 13, 2025	▾
19	MARSHALL WACE, LLP CIK 1318757 · View history	$1.02M 175,862 shares	0.00%	-52.56K(-23.00%)Reduced	SEC filing ↗ Aug 13, 2025	▾
20	BlackRock, Inc. CIK 2012383 · View history	$975.76K 168,235 shares	0.00%	-12.20K(-6.80%)Reduced	SEC filing ↗ Aug 12, 2025	▾

Showing 20 / 56 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

19,759,651

Not deduplicated across managers

Disclosed value

$108.04M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Silence Therapeutics plc · Q2 2025

Explore all 56 reporting institutions.

This page includes 20 of 56 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.