Taysha Gene Therapies, Inc. TSHA
CIK 0001806310 · CUSIP 877619106
Quarter-end disclosures, not live holdings.
Top 20 institutions
Weight means this stock's share of the manager's own portfolio.
| # | Manager | Value | Manager weight | Change vs prior | Source | |
|---|---|---|---|---|---|---|
| 01 | RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history | $105.29M 23,555,648 shares | 1.12% | 0(0.0%)Unchanged | SEC filing ↗ May 15, 2026 | ▾ |
| 02 | GOLDMAN SACHS GROUP INC CIK 886982 · View history | $99.99M 22,369,645 shares | 0.01% | +8.68M(+63.4%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 03 | Avoro Capital Advisors LLC CIK 1633313 · View history | $97.00M 21,700,000 shares | 0.96% | 0(0.0%)Unchanged | SEC filing ↗ May 15, 2026 | ▾ |
| 04 | BlackRock, Inc. CIK 2012383 · View history | $82.09M 18,365,608 shares | 0.00% | -277.52K(-1.5%)Reduced | SEC filing ↗ May 13, 2026 | ▾ |
| 05 | Vestal Point Capital, LP CIK 1974915 · View history | $80.46M 18,000,000 shares | 2.25% | +4.25M(+30.9%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 06 | MORGAN STANLEY CIK 895421 · View history | $80.31M 17,965,371 shares | 0.00% | -113.15K(-0.6%)Reduced | SEC filing ↗ May 15, 2026 | ▾ |
| 07 | FMR LLC CIK 315066 · View history | $64.02M 14,321,255 shares | 0.00% | +792.89K(+5.9%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 08 | RTW INVESTMENTS, LP CIK 1493215 · View history | $61.15M 13,680,248 shares | 0.61% | -2.72M(-16.6%)Reduced | SEC filing ↗ May 15, 2026 | ▾ |
| 09 | STATE STREET CORP CIK 93751 · View history | $50.10M 11,209,078 shares | 0.00% | +418.99K(+3.9%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 10 | VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · Amended · View history | $45.73M 10,231,502 shares | 0.00% | — | SEC filing ↗ May 15, 2026 | ▾ |
| 11 | Octagon Capital Advisors LP CIK 1839435 · View history | $39.60M 8,859,911 shares | 4.38% | 0(0.0%)Unchanged | SEC filing ↗ May 15, 2026 | ▾ |
| 12 | Siren, L.L.C. CIK 2005245 · View history | $39.47M 8,829,913 shares | 1.09% | -1.30M(-12.8%)Reduced | SEC filing ↗ May 14, 2026 | ▾ |
| 13 | Polar Capital Holdings Plc CIK 1837309 · View history | $25.27M 5,654,340 shares | 0.11% | -2.28M(-28.7%)Reduced | SEC filing ↗ May 15, 2026 | ▾ |
| 14 | GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history | $24.73M 5,531,955 shares | 0.00% | +144.93K(+2.7%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 15 | GordonMD Global Investments LP CIK 2039349 · View history | $22.22M 737,550 shares | 15.47% | -593.35K(-44.6%)Reduced | SEC filing ↗ May 15, 2026 | ▾ |
| 16 | D. E. Shaw & Co., Inc. CIK 1009207 · View history | $19.79M 4,427,301 shares | 0.02% | +413.67K(+10.3%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 17 | BAKER BROS. ADVISORS LP CIK 1263508 · View history | $17.90M 4,004,756 shares | 0.10% | 0(0.0%)Unchanged | SEC filing ↗ May 15, 2026 | ▾ |
| 18 | MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history | $14.67M 3,281,820 shares | 0.01% | +102.96K(+3.2%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 19 | Casdin Capital, LLC CIK 1534261 · View history | $14.53M 3,250,000 shares | 1.10% | +1.75M(+116.7%)Added | SEC filing ↗ May 15, 2026 | ▾ |
| 20 | ADAR1 Capital Management, LLC CIK 1940272 · View history | $13.32M 2,979,429 shares | 0.80% | +483.62K(+19.4%)Added | SEC filing ↗ May 18, 2026 | ▾ |
Showing 20 / 191 institutions. The complete set is available through the API.
Coverage & totals by quarter
Reporting institutions by quarter
Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.
Explore all 191 reporting institutions.
This page includes 20 of 191 reporting institutions. Sign in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.
- Download CSV
- Earlier quarters
- Advanced screening & filtering
- API & AI access
+ New accounts get free API credits to explore data beyond ownership filings.
For AI agents & developers
The initial HTML of this page carries its exact data as script#research-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 20 of 191 reporting institutions; totals use the complete disclosed data.
Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP.
MCP https://api.akkrudata.ai/mcp
get_institutional_security_holders
{"cusip":"877619106","quarter":"2026Q1","type":"positions","page_size":100}Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.
- MCP endpoint
- https://api.akkrudata.ai/mcp
- API / MCP documentation
- /documents
- llms.txt
- /llms.txt
Sources, coverage & how to read this data
Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.