Company · Ownership research

Wave Life Sciences, Inc. WVE

CIK 0001631574 · CUSIP Y95308105

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP Y95308105 (WVE), not CUSIP Y95308955 (WVE), CUSIP Y95308905 (WVE), CUSIP 94352A104 (WVE), CUSIP G8994E106 (WVE), and does not merge CUSIPs.

This page lists the top 20 of 220 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	GSK plc CIK 1131399 · View history	$310.18M 18,245,691 shares	38.82%	—	SEC filing ↗ Feb 12, 2026	▾
02	RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history	$309.45M 18,203,009 shares	3.17%	+1.00K(0.00%)Added	SEC filing ↗ Feb 17, 2026	▾
03	FMR LLC CIK 315066 · View history	$257.31M 15,135,983 shares	0.01%	+10.01M(+195.00%)Added	SEC filing ↗ Feb 17, 2026	▾
04	BlackRock, Inc. CIK 2012383 · View history	$215.03M 12,648,907 shares	0.00%	+2.22M(+21.30%)Added	SEC filing ↗ Feb 12, 2026	▾
05	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$166.36M 9,786,061 shares	0.25%	-4.78M(-32.80%)Reduced	SEC filing ↗ Feb 17, 2026	▾
06	MAVERICK CAPITAL LTD CIK 934639 · View history	$157.76M 9,280,237 shares	1.69%	+888.38K(+10.60%)Added	SEC filing ↗ Feb 13, 2026	▾
07	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$125.93M 7,407,372 shares	0.01%	+3.36M(+83.10%)Added	SEC filing ↗ Feb 17, 2026	▾
08	Darwin Global Management, Ltd. CIK 1839209 · View history	$125.17M 7,298,421 shares	2.53%	+7.30MNew	SEC filing ↗ Feb 17, 2026	▾
09	Driehaus Capital Management LLC CIK 938206 · View history	$111.88M 6,581,067 shares	0.76%	+283.01K(+4.50%)Added	SEC filing ↗ Feb 17, 2026	▾
10	M28 Capital Management LP CIK 1807489 · View history	$96.30M 5,664,548 shares	70.00%	0(0.00%)Unchanged	SEC filing ↗ Feb 13, 2026	▾
11	FEDERATED HERMES, INC. CIK 1056288 · View history	$80.66M 4,744,520 shares	0.13%	+993.83K(+26.50%)Added	SEC filing ↗ Feb 12, 2026	▾
12	PRIMECAP MANAGEMENT CO/CA/ CIK 763212 · View history	$69.62M 4,095,282 shares	0.05%	+2.20M(+115.70%)Added	SEC filing ↗ Feb 11, 2026	▾
13	683 Capital Management, LLC CIK 1404574 · View history	$68.25M 4,015,000 shares	5.68%	-135.00K(-3.30%)Reduced	SEC filing ↗ Feb 17, 2026	▾
14	VANGUARD GROUP INC CIK 102909 · View history	$60.75M 3,573,746 shares	0.00%	+433.91K(+13.80%)Added	SEC filing ↗ Jan 29, 2026	▾
15	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$53.90M 3,170,110 shares	0.00%	+251.74K(+8.60%)Added	SEC filing ↗ Feb 9, 2026	▾
16	STATE STREET CORP CIK 93751 · View history	$50.93M 2,996,084 shares	0.00%	+149.72K(+5.30%)Added	SEC filing ↗ Feb 13, 2026	▾
17	GOLDMAN SACHS GROUP INC CIK 886982 · Amended · View history	$48.52M 2,854,082 shares	0.01%	+728.95K(+34.30%)Added	SEC filing ↗ Mar 25, 2026	▾
18	Affinity Asset Advisors, LLC CIK 1773195 · View history	$45.90M 2,700,000 shares	3.30%	+600.00K(+28.60%)Added	SEC filing ↗ Feb 13, 2026	▾
19	EMERALD ADVISERS, LLC CIK 1015083 · View history	$41.74M 2,455,089 shares	1.29%	-541.81K(-18.10%)Reduced	SEC filing ↗ Feb 9, 2026	▾
20	Siren, L.L.C. CIK 2005245 · View history	$41.65M 2,450,000 shares	1.24%	-1.25M(-33.70%)Reduced	SEC filing ↗ Feb 13, 2026	▾

Showing 20 / 220 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

220

Cancelled or null records excluded

Disclosed shares

182,748,682

Not deduplicated across managers

Disclosed value

$3.11B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Wave Life Sciences, Inc. · Q4 2025

Explore all 220 reporting institutions.

This page includes 20 of 220 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

Download CSV
Earlier quarters
Advanced screening & filtering
API & AI access

Already have an account?

＋ New accounts get free API credits to explore data beyond ownership filings.

For AI agents & developers

The initial HTML of this page carries its exact data as script#research-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 20 of 220 reporting institutions; totals use the complete disclosed data.

Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP / CLI.

MCP  https://api.akkrudata.ai/mcp

akkru_institutional_holdings
{"action":"holders","cusip":"Y95308105","quarter":"2025Q4","type":"positions","page_size":100}

Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.

MCP endpoint: https://api.akkrudata.ai/mcp
API / MCP / CLI documentation: /documents
llms.txt: /llms.txt

Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.