Sofinnova Investments, Inc.
CIK 1631134 · Holdings on Jun 30, 2026 · First reported Aug 14, 2026
Top ten holdings
Q2 2026- NTRA22.48%
- VERA6.40%
- GMAB5.94%
- JAZZ4.70%
- RAPP4.24%
- SPTX4.14%
- AVBP3.15%
- RARE3.06%
- BIOA3.00%
- BMY2.70%
Share classes counted separately59.81%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- NTRAWeight increased · +6.95 pp15.53% → 22.48%Shares 0 (0.00%)
- GMABWeight increased · +4.93 pp1.01% → 5.94%Shares +3.29M (+437.74%)
- BMYWeight decreased · -3.34 pp6.04% → 2.70%Shares -1.11M (-55.90%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 26
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | NTRANATERA INC View history and evidence | $420.82M | 22.48% | 1.55M shares | 15.53% → 22.48%+6.95 pp 0 (0.00%) | Unchanged | ▾ |
| 02 | VERAVERA THERAPEUTICS INCCL A View history and evidence | $119.89M | 6.40% | 2.79M shares | 5.63% → 6.40%+0.77 pp 0 (0.00%) | Unchanged | ▾ |
| 03 | GMABGENMAB A/S -SP ADRSPONSORED ADS View history and evidence | $111.12M | 5.94% | 4.05M shares | 1.01% → 5.94%+4.93 pp +3.29M (+437.74%) | Added | ▾ |
| 04 | JAZZJAZZ PHARMACEUTICALS PLCSHS USD View history and evidence | $88.04M | 4.70% | 365.34K shares | 5.67% → 4.70%-0.97 pp -232.99K (-38.94%) | Reduced | ▾ |
| 05 | RAPPRAPPORT THERAPEUTICS INC View history and evidence | $79.36M | 4.24% | 1.90M shares | 2.99% → 4.24%+1.25 pp 0 (0.00%) | Unchanged | ▾ |
| 06 | SPTXSEAPORT THERAPEUTICS INC View history and evidence | $77.43M | 4.14% | 3.56M shares | Prior unavailable +3.56M | New | ▾ |
| 07 | AVBPARRIVENT BIOPHARMA INC View history and evidence | $58.95M | 3.15% | 1.70M shares | 1.96% → 3.15%+1.19 pp 0 (0.00%) | Unchanged | ▾ |
| 08 | RAREULTRAGENYX PHARMACEUTICAL IN View history and evidence | $57.35M | 3.06% | 1.72M shares | 3.30% → 3.06%-0.24 pp -1.43M (-45.40%) | Reduced | ▾ |
| 09 | BIOABIOAGE LABS INC View history and evidence | $56.22M | 3.00% | 2.29M shares | 2.01% → 3.00%+0.99 pp 0 (0.00%) | Unchanged | ▾ |
| 10 | BMYBRISTOL-MYERS SQUIBB CO View history and evidence | $50.53M | 2.70% | 876.97K shares | 6.04% → 2.70%-3.34 pp -1.11M (-55.90%) | Reduced | ▾ |
Options overlay 4
$62.24M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
RAREULTRAGENYX PHARMACEUTICAL IN View history and evidence | Call | 500.00K | $16.70M | +150.00K (+42.86%) | ▾ |
ISRGINTUITIVE SURGICAL INCCOM NEW View history and evidence | Call | 40.00K | $15.91M | +40.00K | ▾ |
GMEDGLOBUS MEDICAL INC - ACL A View history and evidence | Call | 200.00K | $15.80M | +200.00K | ▾ |
3 / 4 options · preview only
Exited positions 30
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| IWM ISHARES RUSSELL 2000 ETF | Put | -600,000 | -$148.80M | SEC filing ↗ | SEC filing ↗ |
| XBI SS SPDR S&P BIOTECH ETF | Put | -1,050,000 | -$134.12M | SEC filing ↗ | SEC filing ↗ |
| AZN ASTRAZENECA PLC | Non-derivative | -456,031 | -$89.94M | SEC filing ↗ | SEC filing ↗ |
3 / 30 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1631134 · Period 2026-06-30
Data loaded 2026-09-23 · First reported 2026-08-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 1934262135
}Research all 57 reported holdings.
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