Sofinnova Investments, Inc.
CIK 1631134 · Holdings on Mar 31, 2025 · First reported May 15, 2025
Top ten holdings
Q1 2025- NTRA16.53%
- SYK8.38%
- VERA5.06%
- JAZZ4.78%
- MDT3.82%
- ALNY3.59%
- GILD3.54%
- LLY3.29%
- IDYA3.24%
- SLNO2.61%
Share classes counted separately54.84%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- SYKWeight increased · +5.32 pp3.06% → 8.38%Shares +182.56K (+157.37%)
- VERAWeight decreased · -3.60 pp8.66% → 5.06%Shares 0 (0.00%)
- LLYWeight increased · +2.48 pp0.81% → 3.29%Shares +38.44K (+267.59%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 25
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | NTRANATERA INC View history and evidence | $219.23M | 16.53% | 1.55M shares | 17.99% → 16.53%-1.46 pp 0 (0.00%) | Unchanged | ↗▾ |
| 02 | SYKSTRYKER CORP View history and evidence | $111.14M | 8.38% | 298.57K shares | 3.06% → 8.38%+5.32 pp +182.56K (+157.37%) | Added | ↗▾ |
| 03 | VERAVERA THERAPEUTICS INCCL A View history and evidence | $67.11M | 5.06% | 2.79M shares | 8.66% → 5.06%-3.60 pp 0 (0.00%) | Unchanged | ↗▾ |
| 04 | JAZZJAZZ PHARMACEUTICALS PLCSHS USD View history and evidence | $63.32M | 4.78% | 510.05K shares | 4.55% → 4.78%+0.23 pp +5.86K (+1.16%) | Added | ↗▾ |
| 05 | MDTMEDTRONIC PLCSHS View history and evidence | $50.59M | 3.82% | 562.99K shares | Prior unavailable +562.99K | New | ↗▾ |
| 06 | ALNYALNYLAM PHARMACEUTICALS INC View history and evidence | $47.57M | 3.59% | 176.18K shares | 1.90% → 3.59%+1.69 pp +66.02K (+59.94%) | Added | ↗▾ |
| 07 | GILDGILEAD SCIENCES INC View history and evidence | $46.94M | 3.54% | 418.90K shares | 5.24% → 3.54%-1.70 pp -355.33K (-45.89%) | Reduced | ↗▾ |
| 08 | LLYELI LILLY & CO View history and evidence | $43.61M | 3.29% | 52.80K shares | 0.81% → 3.29%+2.48 pp +38.44K (+267.59%) | Added | ↗▾ |
| 09 | IDYAIDEAYA BIOSCIENCES INC View history and evidence | $42.95M | 3.24% | 2.62M shares | 2.01% → 3.24%+1.23 pp +1.55M (+145.27%) | Added | ↗▾ |
| 10 | SLNOSOLENO THERAPEUTICS INC View history and evidence | $34.62M | 2.61% | 484.47K shares | 2.49% → 2.61%+0.12 pp -272.78K (-36.02%) | Reduced | ↗▾ |
Options overlay 5
$205.05M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
QQQINVESCO QQQ TRUST SERIES 1UNIT SER 1 View history and evidence | Put | 175.00K | $82.06M | +175.00K | ▾ |
IWMISHARES RUSSELL 2000 ETFRUSSELL 2000 ETF View history and evidence | Put | 350.00K | $69.82M | +350.00K | ▾ |
SLNOSOLENO THERAPEUTICS INC View history and evidence | Put | 529.30K | $37.82M | +529.30K | ▾ |
3 / 5 options · preview only
Exited positions 17
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| ABBV ABBVIE INC | Non-derivative | -359,393 | -$63.86M | SEC filing ↗ | SEC filing ↗ |
| AZNN ASTRAZENECA PLC-SPONS ADR | Non-derivative | -651,344 | -$42.68M | SEC filing ↗ | SEC filing ↗ |
| BSX BOSTON SCIENTIFIC CORP | Non-derivative | -346,571 | -$30.96M | SEC filing ↗ | SEC filing ↗ |
3 / 17 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1631134 · Period 2025-03-31
Data loaded 2026-09-23 · First reported 2025-05-15
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 1531129746
}Research all 64 reported holdings.
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