Octagon Capital Advisors LP
CIK 1839435 · Holdings on Dec 31, 2024 · First reported Feb 14, 2025
Top ten holdings
Q4 2024- APLS16.32%
- AVBP9.33%
- DNTH7.82%
- CNTA5.68%
- VRNA4.51%
- NUVB4.16%
- INSM3.90%
- COGT3.67%
- SRRK3.59%
- 60255C8853.57%
Share classes counted separately62.55%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- VRNAWeight decreased · -3.94 pp8.45% → 4.51%Shares -1.26M (-68.87%)
- APLSWeight increased · +2.44 pp13.88% → 16.32%Shares 0 (0.00%)
- AVBPWeight increased · +1.89 pp7.44% → 9.33%Shares +83.00K (+4.20%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 28
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | APLSAPELLIS PHARMACEUTICALS INC View history and evidence | $95.95M | 16.32% | 3.01M shares | 13.88% → 16.32%+2.44 pp 0 (0.00%) | Unchanged | ↗▾ |
| 02 | AVBPARRIVENT BIOPHARMA INC View history and evidence | $54.86M | 9.33% | 2.06M shares | 7.44% → 9.33%+1.89 pp +83.00K (+4.20%) | Added | ↗▾ |
| 03 | DNTHDIANTHUS THERAPEUTICS INC View history and evidence | $46.00M | 7.82% | 2.11M shares | 7.66% → 7.82%+0.16 pp +363.50K (+20.81%) | Added | ↗▾ |
| 04 | CNTACENTESSA PHARMACEUTICALS-ADRSPONSORED ADS View history and evidence | $33.38M | 5.68% | 1.99M shares | 5.15% → 5.68%+0.53 pp -19.00K (-0.94%) | Reduced | ↗▾ |
| 05 | VRNAVERONA PHARMA PLC - ADRSPONSORED ADS View history and evidence | $26.53M | 4.51% | 571.26K shares | 8.45% → 4.51%-3.94 pp -1.26M (-68.87%) | Reduced | ↗▾ |
| 06 | NUVBNUVATION BIO INCCOM CL A View history and evidence | $24.48M | 4.16% | 9.20M shares | 4.46% → 4.16%-0.30 pp -2.97M (-24.39%) | Reduced | ↗▾ |
| 07 | INSMINSMED INCCOM PAR View history and evidence | $22.92M | 3.90% | 332.00K shares | 5.10% → 3.90%-1.20 pp -104.82K (-24.00%) | Reduced | ↗▾ |
| 08 | COGTCOGENT BIOSCIENCES INC View history and evidence | $21.55M | 3.67% | 2.76M shares | 2.26% → 3.67%+1.41 pp +1.46M (+111.72%) | Added | ↗▾ |
| 09 | SRRKSCHOLAR ROCK HOLDING CORP View history and evidence | $21.09M | 3.59% | 488.00K shares | Prior unavailable +488.00K | New | ↗▾ |
| 10 | 60255C885MIND MEDICINE MINDMED INCCOM NEW View history and evidence | $21.01M | 3.57% | 3.02M shares | 2.75% → 3.57%+0.82 pp 0 (0.00%) | Unchanged | ↗▾ |
Options overlay 2
$19.81M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
INSMINSMED INCCOM PAR View history and evidence | Call | 250.00K | $17.26M | 0 (0.00%) | ▾ |
CNTACENTESSA PHARMACEUTICALS-ADRSPONSORED ADS View history and evidence | Put | 152.00K | $2.55M | +152.00K | ▾ |
2 / 2 options · preview only
Exited positions 16
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| GPCR STRUCTURE THERAPEUTICS INC | Non-derivative | -1,198,000 | -$52.58M | SEC filing ↗ | SEC filing ↗ |
| EYPT EYEPOINT INC | Non-derivative | -1,093,503 | -$8.74M | SEC filing ↗ | SEC filing ↗ |
| PRAX PRAXIS PRECISION MEDICINES I | Non-derivative | -130,000 | -$7.48M | SEC filing ↗ | SEC filing ↗ |
3 / 16 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1839435 · Period 2024-12-31
Data loaded 2026-09-23 · First reported 2025-02-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 607700826
}Research all 33 reported holdings.
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