Octagon Capital Advisors LP
CIK 1839435 · Holdings on Sep 30, 2025 · First reported Nov 14, 2025
Top ten holdings
Q3 2025- ABVX17.56%
- DNTH14.84%
- GOSS7.00%
- COGT6.44%
- AVBP5.68%
- OCUL4.79%
- TSHA4.63%
- MRUS4.53%
- TRVI4.02%
- 60255C8853.92%
Share classes counted separately73.41%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- ABVXWeight increased · +15.43 pp2.13% → 17.56%Shares +58.00K (+4.58%)
- DNTHWeight increased · +5.27 pp9.57% → 14.84%Shares +75.00K (+3.20%)
- AVBPWeight decreased · -3.62 pp9.30% → 5.68%Shares +25.00K (+1.28%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 26
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | ABVXABIVAX SA-ADRSPONSORED ADS View history and evidence | $112.49M | 17.56% | 1.32M shares | 2.13% → 17.56%+15.43 pp +58.00K (+4.58%) | Added | ↗▾ |
| 02 | DNTHDIANTHUS THERAPEUTICS INC View history and evidence | $95.10M | 14.84% | 2.42M shares | 9.57% → 14.84%+5.27 pp +75.00K (+3.20%) | Added | ↗▾ |
| 03 | GOSSGOSSAMER BIO INC View history and evidence | $44.84M | 7.00% | 17.05M shares | 4.95% → 7.00%+2.05 pp -1.30M (-7.08%) | Reduced | ↗▾ |
| 04 | COGTCOGENT BIOSCIENCES INC View history and evidence | $41.27M | 6.44% | 2.87M shares | 4.35% → 6.44%+2.09 pp +111.11K (+4.02%) | Added | ↗▾ |
| 05 | AVBPARRIVENT BIOPHARMA INC View history and evidence | $36.37M | 5.68% | 1.97M shares | 9.30% → 5.68%-3.62 pp +25.00K (+1.28%) | Added | ↗▾ |
| 06 | OCULOCULAR THERAPEUTIX INC View history and evidence | $30.67M | 4.79% | 2.62M shares | 4.94% → 4.79%-0.15 pp +199.00K (+8.21%) | Added | ↗▾ |
| 07 | TSHATAYSHA GENE THERAPIES INCCOM SHS View history and evidence | $29.65M | 4.63% | 9.07M shares | 6.38% → 4.63%-1.75 pp -3.52M (-27.99%) | Reduced | ↗▾ |
| 08 | MRUSMERUS NV View history and evidence | $29.00M | 4.53% | 308.00K shares | 4.49% → 4.53%+0.04 pp -81.00K (-20.82%) | Reduced | ↗▾ |
| 09 | TRVITREVI THERAPEUTICS INC View history and evidence | $25.76M | 4.02% | 2.81M shares | 4.41% → 4.02%-0.39 pp -857.00K (-23.34%) | Reduced | ↗▾ |
| 10 | 60255C885MIND MEDICINE MINDMED INCCOM NEW View history and evidence | $25.11M | 3.92% | 2.13M shares | 3.03% → 3.92%+0.89 pp 0 (0.00%) | Unchanged | ↗▾ |
Options overlay 1
$19.15M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
CDTXCIDARA THERAPEUTICS INCCOM NEW View history and evidence | Call | 200.00K | $19.15M | +200.00K | ▾ |
1 / 1 options · preview only
Exited positions 7
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| VRNA VERONA PHARMA PLC - ADR | Non-derivative | -337,000 | -$31.87M | SEC filing ↗ | SEC filing ↗ |
| SPRY ARS PHARMACEUTICALS INC | Non-derivative | -1,350,000 | -$23.56M | SEC filing ↗ | SEC filing ↗ |
| ATYR ATYR PHARMA INC | Non-derivative | -3,820,000 | -$19.37M | SEC filing ↗ | SEC filing ↗ |
3 / 7 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1839435 · Period 2025-09-30
Data loaded 2026-09-23 · First reported 2025-11-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 659757896
}Take these holdings further.
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