Company · Ownership research

ANAPTYSBIO, INC ANAB

CIK 0001370053 · CUSIP 032724106

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 032724106 (ANAB), not CUSIP 032724906 (ANAB), CUSIP 032724956 (ANAB), and does not merge CUSIPs.

This page lists the top 20 of 179 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$382.03M 7,880,094 shares	17.44%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
02	Point72 Asset Management, L.P. CIK 1603466 · View history	$93.71M 1,932,890 shares	0.15%	-332.64K(-14.70%)Reduced	SEC filing ↗ Feb 17, 2026	▾
03	BlackRock, Inc. CIK 2012383 · View history	$84.09M 1,734,430 shares	0.00%	+12.11K(+0.70%)Added	SEC filing ↗ Feb 12, 2026	▾
04	VANGUARD GROUP INC CIK 102909 · View history	$74.85M 1,544,037 shares	0.00%	+67.05K(+4.50%)Added	SEC filing ↗ Jan 29, 2026	▾
05	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$64.58M 1,332,087 shares	3.19%	-1.55K(-0.10%)Reduced	SEC filing ↗ Feb 17, 2026	▾
06	STATE STREET CORP CIK 93751 · View history	$51.07M 1,053,474 shares	0.00%	+180.04K(+20.60%)Added	SEC filing ↗ Feb 13, 2026	▾
07	MORGAN STANLEY CIK 895421 · Amended · View history	$50.16M 1,034,562 shares	0.00%	-521.70K(-33.50%)Reduced	SEC filing ↗ May 27, 2026	▾
08	Sanofi CIK 1121404 · View history	$39.85M 821,917 shares	12.84%	0(0.00%)Unchanged	SEC filing ↗ Feb 11, 2026	▾
09	MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history	$39.44M 813,571 shares	0.03%	-705.66K(-46.40%)Reduced	SEC filing ↗ Feb 17, 2026	▾
10	Palo Alto Investors LP CIK 1306923 · View history	$33.45M 690,032 shares	4.66%	+16.51K(+2.50%)Added	SEC filing ↗ Feb 17, 2026	▾
11	D. E. Shaw & Co., Inc. CIK 1009207 · View history	$32.50M 670,288 shares	0.02%	+320.93K(+91.90%)Added	SEC filing ↗ Feb 17, 2026	▾
12	683 Capital Management, LLC CIK 1404574 · View history	$31.42M 648,093 shares	2.61%	+101.09K(+18.50%)Added	SEC filing ↗ Feb 17, 2026	▾
13	First Light Asset Management, LLC CIK 1600004 · View history	$31.33M 646,238 shares	2.40%	-343.92K(-34.70%)Reduced	SEC filing ↗ Feb 17, 2026	▾
14	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP CIK 1164508 · View history	$27.14M 559,744 shares	0.02%	+189.29K(+51.10%)Added	SEC filing ↗ Feb 13, 2026	▾
15	Woodline Partners LP CIK 1784547 · View history	$24.29M 501,023 shares	0.09%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
16	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$22.77M 469,494 shares	0.00%	-4.13K(-0.90%)Reduced	SEC filing ↗ Feb 9, 2026	▾
17	Affinity Asset Advisors, LLC CIK 1773195 · View history	$21.56M 444,692 shares	1.55%	+444.69KNew	SEC filing ↗ Feb 13, 2026	▾
18	GOLDMAN SACHS GROUP INC CIK 886982 · Amended · View history	$19.34M 398,914 shares	0.00%	+69.09K(+20.90%)Added	SEC filing ↗ Mar 25, 2026	▾
19	TWO SIGMA ADVISERS, LP CIK 1478735 · View history	$17.29M 356,700 shares	0.03%	-17.00K(-4.50%)Reduced	SEC filing ↗ Feb 17, 2026	▾
20	Nuveen, LLC CIK 1871926 · View history	$15.35M 316,685 shares	0.00%	-22.59K(-6.70%)Reduced	SEC filing ↗ Feb 12, 2026	▾

Showing 20 / 179 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

179

Cancelled or null records excluded

Disclosed shares

29,354,491

Not deduplicated across managers

Disclosed value

$1.42B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

ANAPTYSBIO, INC · Q4 2025

Explore all 179 reporting institutions.

This page includes 20 of 179 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.