Company · Ownership research

INSMED Inc INSM

CIK 0001104506 · CUSIP 457669307

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 457669307 (INSM), not CUSIP 457669907 (INSM), CUSIP 457669957 (INSM), and does not merge CUSIPs.

This page lists the top 20 of 444 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	VANGUARD GROUP INC CIK 102909 · View history	$1.39B 18,268,122 shares	0.03%	+49.15K(+0.30%)Added	SEC filing ↗ May 9, 2025	▾
02	BlackRock, Inc. CIK 2012383 · View history	$1.22B 16,048,882 shares	0.03%	+15.94K(+0.10%)Added	SEC filing ↗ May 2, 2025	▾
03	Darwin Global Management, Ltd. CIK 1839209 · View history	$1.20B 15,397,975 shares	82.08%	+2.44M(+18.80%)Added	SEC filing ↗ May 15, 2025	▾
04	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$985.94M 12,923,541 shares	0.12%	+219.13K(+1.70%)Added	SEC filing ↗ May 14, 2025	▾
05	Capital International Investors CIK 1562230 · View history	$549.17M 7,198,485 shares	0.11%	+81.49K(+1.10%)Added	SEC filing ↗ May 12, 2025	▾
06	JPMORGAN CHASE & CO CIK 19617 · View history	$484.75M 6,354,022 shares	0.04%	+3.07M(+93.40%)Added	SEC filing ↗ May 12, 2025	▾
07	STATE STREET CORP CIK 93751 · View history	$438.46M 5,747,293 shares	0.02%	-358.86K(-5.90%)Reduced	SEC filing ↗ May 15, 2025	▾
08	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$410.49M 5,380,626 shares	4.54%	+373.76K(+7.50%)Added	SEC filing ↗ May 15, 2025	▾
09	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$327.26M 4,288,735 shares	0.03%	+201.59K(+4.90%)Added	SEC filing ↗ May 13, 2025	▾
10	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$262.97M 3,446,944 shares	0.49%	+1.80M(+109.20%)Added	SEC filing ↗ May 15, 2025	▾
11	FMR LLC CIK 315066 · View history	$258.96M 3,394,384 shares	0.02%	-1.46M(-30.10%)Reduced	SEC filing ↗ May 12, 2025	▾
12	Artisan Partners Limited Partnership CIK 1466153 · View history	$245.45M 3,217,268 shares	0.40%	+90.93K(+2.90%)Added	SEC filing ↗ May 14, 2025	▾
13	RTW INVESTMENTS, LP CIK 1493215 · View history	$229.98M 3,014,558 shares	3.52%	0(0.00%)Unchanged	SEC filing ↗ May 15, 2025	▾
14	AMERIPRISE FINANCIAL INC CIK 820027 · View history	$225.17M 2,951,622 shares	0.06%	+101.53K(+3.60%)Added	SEC filing ↗ May 14, 2025	▾
15	ALLIANCEBERNSTEIN L.P. CIK 1109448 · View history	$184.89M 2,423,513 shares	0.07%	+59.95K(+2.50%)Added	SEC filing ↗ May 15, 2025	▾
16	FIL Ltd CIK 318989 · View history	$182.35M 2,390,201 shares	0.17%	-247.96K(-9.40%)Reduced	SEC filing ↗ May 12, 2025	▾
17	MACQUARIE GROUP LTD CIK 1418333 · Amended · View history	$180.21M 2,362,105 shares	0.22%	+48.95K(+2.10%)Added	SEC filing ↗ Aug 14, 2025	▾
18	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC CIK 1644956 · View history	$176.48M 2,313,217 shares	0.50%	-120.23K(-4.90%)Reduced	SEC filing ↗ May 9, 2025	▾
19	FRANKLIN RESOURCES INC CIK 38777 · View history	$163.89M 2,148,284 shares	0.05%	-11.82K(-0.50%)Reduced	SEC filing ↗ May 13, 2025	▾
20	Holocene Advisors, LP CIK 1700574 · View history	$154.60M 2,026,422 shares	0.46%	+1.34M(+194.70%)Added	SEC filing ↗ May 15, 2025	▾

Showing 20 / 444 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

444

Cancelled or null records excluded

Disclosed shares

200,019,304

Not deduplicated across managers

Disclosed value

$15.31B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

INSMED Inc · Q1 2025

Explore all 444 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.