Company · Ownership research

INSMED Inc INSM

CIK 0001104506 · CUSIP 457669307

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 457669307 (INSM), not CUSIP 457669907 (INSM), CUSIP 457669957 (INSM), and does not merge CUSIPs.

This page lists the top 20 of 677 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	JPMORGAN CHASE & CO CIK 19617 · View history	$4.04B 23,199,512 shares	0.27%	+151.84K(+0.70%)Added	SEC filing ↗ Feb 11, 2026	▾
02	VANGUARD GROUP INC CIK 102909 · View history	$3.67B 21,076,344 shares	0.05%	+1.14M(+5.70%)Added	SEC filing ↗ Jan 29, 2026	▾
03	Darwin Global Management, Ltd. CIK 1839209 · View history	$3.64B 20,933,277 shares	73.78%	+475.83K(+2.30%)Added	SEC filing ↗ Feb 17, 2026	▾
04	BlackRock, Inc. CIK 2012383 · View history	$2.62B 15,065,052 shares	0.04%	+2.70M(+21.80%)Added	SEC filing ↗ Feb 12, 2026	▾
05	FMR LLC CIK 315066 · View history	$1.73B 9,927,936 shares	0.09%	+746.97K(+8.10%)Added	SEC filing ↗ Feb 17, 2026	▾
06	Invesco Ltd. CIK 914208 · Amended · View history	$1.31B 7,518,338 shares	0.12%	+5.51M(+275.20%)Added	SEC filing ↗SEC filing ↗ Feb 19, 2026	▾
07	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$1.15B 6,592,746 shares	6.72%	-110.74K(-1.70%)Reduced	SEC filing ↗ Feb 17, 2026	▾
08	STATE STREET CORP CIK 93751 · View history	$905.31M 5,201,744 shares	0.03%	+1.22M(+30.60%)Added	SEC filing ↗ Feb 13, 2026	▾
09	Capital International Investors CIK 1562230 · View history	$896.60M 5,151,671 shares	0.14%	-2.40M(-31.80%)Reduced	SEC filing ↗ Feb 11, 2026	▾
10	Artisan Partners Limited Partnership CIK 1466153 · View history	$843.01M 4,843,749 shares	1.29%	-93.93K(-1.90%)Reduced	SEC filing ↗ Feb 17, 2026	▾
11	RTW INVESTMENTS, LP CIK 1493215 · View history	$842.85M 4,842,879 shares	8.44%	+1.76M(+57.00%)Added	SEC filing ↗ Feb 17, 2026	▾
12	D. E. Shaw & Co., Inc. CIK 1009207 · View history	$757.25M 4,350,995 shares	0.58%	-1.31M(-23.10%)Reduced	SEC filing ↗ Feb 17, 2026	▾
13	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$751.94M 4,299,052 shares	0.05%	+539.63K(+14.40%)Added	SEC filing ↗ Feb 9, 2026	▾
14	Orbis Allan Gray Ltd CIK 1663865 · View history	$727.48M 4,179,957 shares	3.05%	+929.09K(+28.60%)Added	SEC filing ↗ Feb 17, 2026	▾
15	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$703.03M 4,039,466 shares	0.08%	-2.89M(-41.70%)Reduced	SEC filing ↗ Feb 17, 2026	▾
16	NORGES BANK CIK 1374170 · View history	$506.63M 2,910,971 shares	0.05%	+2.91MNew	SEC filing ↗ Feb 10, 2026	▾
17	FRANKLIN RESOURCES INC CIK 38777 · View history	$479.57M 2,755,536 shares	0.12%	+615.81K(+28.80%)Added	SEC filing ↗ Feb 11, 2026	▾
18	AMERIPRISE FINANCIAL INC CIK 820027 · View history	$342.66M 1,968,857 shares	0.08%	-753.02K(-27.70%)Reduced	SEC filing ↗ Feb 17, 2026	▾
19	UBS Group AG CIK 1610520 · View history	$325.04M 1,867,635 shares	0.06%	+221.40K(+13.40%)Added	SEC filing ↗ Jan 29, 2026	▾
20	BANK OF AMERICA CORP /DE/ CIK 70858 · View history	$300.34M 1,725,681 shares	0.02%	+123.88K(+7.70%)Added	SEC filing ↗ Feb 17, 2026	▾

Showing 20 / 677 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

677

Cancelled or null records excluded

Disclosed shares

217,365,307

Not deduplicated across managers

Disclosed value

$37.83B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

INSMED Inc · Q4 2025

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This page includes 20 of 677 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.