Company · Ownership research

Krystal Biotech, Inc. KRYS

CIK 0001711279 · CUSIP 501147102

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 501147102 (KRYS), not CUSIP 501147902 (KRYS), CUSIP 501147952 (KRYS), and does not merge CUSIPs.

This page lists the top 20 of 336 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	FMR LLC CIK 315066 · View history	$1.07B 4,349,628 shares	0.05%	+8.18K(+0.20%)Added	SEC filing ↗ Feb 17, 2026	▾
02	BlackRock, Inc. CIK 2012383 · View history	$970.83M 3,937,817 shares	0.02%	+103.69K(+2.70%)Added	SEC filing ↗ Feb 12, 2026	▾
03	Avoro Capital Advisors LLC CIK 1633313 · Amended · View history	$712.23M 2,888,888 shares	7.00%	+111.11K(+4.00%)Added	SEC filing ↗ Mar 16, 2026	▾
04	VANGUARD GROUP INC CIK 102909 · View history	$685.10M 2,778,845 shares	0.01%	-13.36K(-0.50%)Reduced	SEC filing ↗ Jan 29, 2026	▾
05	STATE STREET CORP CIK 93751 · View history	$330.93M 1,342,303 shares	0.01%	-53.66K(-3.80%)Reduced	SEC filing ↗ Feb 13, 2026	▾
06	Soleus Capital Management, L.P. CIK 1802630 · View history	$232.01M 941,059 shares	9.84%	-77.77K(-7.60%)Reduced	SEC filing ↗ Feb 12, 2026	▾
07	Capital World Investors CIK 1422849 · View history	$199.57M 809,500 shares	0.03%	+260(0.00%)Added	SEC filing ↗ Feb 11, 2026	▾
08	Redmile Group, LLC CIK 1425738 · View history	$167.08M 677,705 shares	12.30%	+16.32K(+2.50%)Added	SEC filing ↗ Feb 17, 2026	▾
09	Hood River Capital Management LLC CIK 1578177 · View history	$151.20M 613,302 shares	1.66%	+6.36K(+1.00%)Added	SEC filing ↗ Feb 17, 2026	▾
10	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$150.88M 611,878 shares	0.01%	+634(+0.10%)Added	SEC filing ↗ Feb 9, 2026	▾
11	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$130.66M 529,955 shares	0.01%	+62.90K(+13.50%)Added	SEC filing ↗ Feb 17, 2026	▾
12	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$121.54M 492,968 shares	0.03%	-41.00K(-7.70%)Reduced	SEC filing ↗ Feb 12, 2026	▾
13	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$120.42M 488,460 shares	3.23%	-200.00K(-29.10%)Reduced	SEC filing ↗ Feb 13, 2026	▾
14	Bellevue Group AG CIK 1674546 · View history	$101.16M 410,323 shares	1.92%	+409.01K(+31,174.60%)Added	SEC filing ↗ Feb 17, 2026	▾
15	CITADEL ADVISORS LLC CIK 1423053 · View history	$95.29M 386,505 shares	0.06%	-250.48K(-39.30%)Reduced	SEC filing ↗ Feb 17, 2026	▾
16	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC CIK 1644956 · View history	$92.78M 376,340 shares	0.26%	+227.04K(+152.10%)Added	SEC filing ↗ Feb 9, 2026	▾
17	GOLDMAN SACHS GROUP INC CIK 886982 · Amended · View history	$72.37M 293,525 shares	0.01%	-54.73K(-15.70%)Reduced	SEC filing ↗ Mar 25, 2026	▾
18	NORGES BANK CIK 1374170 · View history	$70.16M 284,573 shares	0.01%	+284.57KNew	SEC filing ↗ Feb 10, 2026	▾
19	NORTHERN TRUST CORP CIK 73124 · View history	$61.00M 247,443 shares	0.01%	-722(-0.30%)Reduced	SEC filing ↗ Feb 17, 2026	▾
20	FIRST TRUST ADVISORS LP CIK 1125816 · View history	$60.47M 245,276 shares	0.04%	-3.12K(-1.30%)Reduced	SEC filing ↗ Feb 13, 2026	▾

Showing 20 / 336 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

336

Cancelled or null records excluded

Disclosed shares

28,425,252

Not deduplicated across managers

Disclosed value

$7.01B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Krystal Biotech, Inc. · Q4 2025

Explore all 336 reporting institutions.

This page includes 20 of 336 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.