Company · Ownership research

Krystal Biotech, Inc. KRYS

CIK 0001711279 · CUSIP 501147102

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 501147102 (KRYS), not CUSIP 501147902 (KRYS), CUSIP 501147952 (KRYS), and does not merge CUSIPs.

This page lists the top 20 of 369 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	FMR LLC CIK 315066 · View history	$1.13B 4,373,987 shares	0.06%	+24.36K(+0.60%)Added	SEC filing ↗ May 15, 2026	▾
02	BlackRock, Inc. CIK 2012383 · View history	$1.02B 3,940,456 shares	0.02%	+2.64K(+0.10%)Added	SEC filing ↗ May 13, 2026	▾
03	Avoro Capital Advisors LLC CIK 1633313 · View history	$746.26M 2,888,888 shares	7.35%	0(0.00%)Unchanged	SEC filing ↗ May 15, 2026	▾
04	VANGUARD PORTFOLIO MANAGEMENT LLC CIK 2100121 · Amended · View history	$376.30M 1,456,727 shares	0.02%	—	SEC filing ↗ May 8, 2026	▾
05	STATE STREET CORP CIK 93751 · View history	$339.54M 1,314,434 shares	0.01%	-27.87K(-2.10%)Reduced	SEC filing ↗ May 15, 2026	▾
06	VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · Amended · View history	$301.03M 1,165,324 shares	0.01%	—	SEC filing ↗ May 15, 2026	▾
07	Soleus Capital Management, L.P. CIK 1802630 · View history	$297.87M 1,153,087 shares	12.06%	+212.03K(+22.50%)Added	SEC filing ↗ May 14, 2026	▾
08	Capital World Investors CIK 1422849 · View history	$213.04M 824,720 shares	0.03%	+15.22K(+1.90%)Added	SEC filing ↗ May 13, 2026	▾
09	Redmile Group, LLC CIK 1425738 · View history	$173.98M 673,505 shares	11.52%	-4.20K(-0.60%)Reduced	SEC filing ↗ May 15, 2026	▾
10	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$166.38M 643,975 shares	0.01%	+32.10K(+5.20%)Added	SEC filing ↗ May 15, 2026	▾
11	Hood River Capital Management LLC CIK 1578177 · View history	$160.05M 619,586 shares	1.60%	+6.28K(+1.00%)Added	SEC filing ↗ May 15, 2026	▾
12	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$125.31M 485,074 shares	0.01%	-44.88K(-8.50%)Reduced	SEC filing ↗ May 15, 2026	▾
13	Bellevue Group AG CIK 1674546 · View history	$124.45M 481,785 shares	2.96%	+71.46K(+17.40%)Added	SEC filing ↗ May 15, 2026	▾
14	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$124.33M 481,307 shares	3.20%	-7.15K(-1.50%)Reduced	SEC filing ↗ May 15, 2026	▾
15	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$121.13M 468,990 shares	0.03%	-23.98K(-4.90%)Reduced	SEC filing ↗ May 7, 2026	▾
16	WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC CIK 1644956 · View history	$105.18M 407,178 shares	0.35%	+30.84K(+8.20%)Added	SEC filing ↗ May 8, 2026	▾
17	FIRST TRUST ADVISORS LP CIK 1125816 · View history	$90.55M 350,521 shares	0.06%	+105.25K(+42.90%)Added	SEC filing ↗ May 13, 2026	▾
18	JANUS HENDERSON GROUP PLC CIK 1274173 · Amended · View history	$68.88M 266,659 shares	0.03%	+47.22K(+21.50%)Added	SEC filing ↗ May 18, 2026	▾
19	BANK OF AMERICA CORP /DE/ CIK 70858 · View history	$67.33M 260,647 shares	0.00%	+69.84K(+36.60%)Added	SEC filing ↗ May 18, 2026	▾
20	NORTHERN TRUST CORP CIK 73124 · View history	$65.22M 252,463 shares	0.01%	+5.02K(+2.00%)Added	SEC filing ↗ May 14, 2026	▾

Showing 20 / 369 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

369

Cancelled or null records excluded

Disclosed shares

28,376,524

Not deduplicated across managers

Disclosed value

$7.32B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Krystal Biotech, Inc. · Q1 2026

Explore all 369 reporting institutions.

This page includes 20 of 369 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.