Company · Ownership research

Maze Therapeutics, Inc. MAZE

CIK 0001842295 · CUSIP 578784100

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 578784100 (MAZE), not CUSIP 578784950 (MAZE), CUSIP 578784900 (MAZE), and does not merge CUSIPs.

This page lists the top 20 of 94 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	TRV GP IV, LLC CIK 1688325 · View history	$157.50M 6,073,958 shares	57.49%	0(0.00%)Unchanged	SEC filing ↗ Nov 13, 2025	▾
02	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$118.43M 4,567,274 shares	3.55%	-1(0.00%)Reduced	SEC filing ↗ Nov 14, 2025	▾
03	ARCH Venture Management, LLC CIK 1274403 · View history	$106.83M 4,120,053 shares	21.70%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
04	Deep Track Capital, LP CIK 1856083 · View history	$102.40M 3,948,910 shares	2.86%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
05	Alphabet Inc. CIK 1652044 · View history	$62.56M 2,412,471 shares	2.60%	0(0.00%)Unchanged	SEC filing ↗ Nov 7, 2025	▾
06	a16z Capital Management, L.L.C. CIK 1540358 · View history	$44.14M 1,702,225 shares	3.16%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
07	Matrix Capital Management Company, LP CIK 1410830 · View history	$42.88M 1,653,684 shares	40.17%	-832.50K(-33.50%)Reduced	SEC filing ↗ Nov 13, 2025	▾
08	VANGUARD GROUP INC CIK 102909 · View history	$34.62M 1,334,955 shares	0.00%	+915.34K(+218.10%)Added	SEC filing ↗ Nov 7, 2025	▾
09	BlackRock, Inc. CIK 2012383 · View history	$34.12M 1,316,016 shares	0.00%	+701.31K(+114.10%)Added	SEC filing ↗ Nov 12, 2025	▾
10	VR Adviser, LLC CIK 1615982 · View history	$31.91M 1,230,769 shares	1.80%	+1.23MNew	SEC filing ↗ Nov 14, 2025	▾
11	Logos Global Management LP CIK 1792126 · View history	$31.82M 1,227,300 shares	3.14%	+615.39K(+100.60%)Added	SEC filing ↗ Nov 14, 2025	▾
12	General Catalyst Group Management, LLC CIK 1637946 · View history	$26.86M 1,035,910 shares	0.88%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
13	Woodline Partners LP CIK 1784547 · View history	$26.84M 1,035,229 shares	0.13%	+94.53K(+10.00%)Added	SEC filing ↗ Nov 14, 2025	▾
14	TRV GP V, LLC CIK 1990717 · View history	$24.65M 950,800 shares	6.97%	0(0.00%)Unchanged	SEC filing ↗ Nov 13, 2025	▾
15	MARSHALL WACE, LLP CIK 1318757 · View history	$20.17M 777,701 shares	0.02%	+758.10K(+3,868.50%)Added	SEC filing ↗ Nov 13, 2025	▾
16	Casdin Capital, LLC CIK 1534261 · View history	$19.68M 758,857 shares	1.64%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
17	JANUS HENDERSON GROUP PLC CIK 1274173 · View history	$19.49M 751,874 shares	0.01%	-649.39K(-46.30%)Reduced	SEC filing ↗ Nov 14, 2025	▾
18	Ikarian Capital, LLC CIK 1778253 · View history	$19.21M 740,825 shares	3.89%	+478.08K(+182.00%)Added	SEC filing ↗ Nov 14, 2025	▾
19	FMR LLC CIK 315066 · View history	$17.00M 655,614 shares	0.00%	+101.08K(+18.20%)Added	SEC filing ↗ Nov 13, 2025	▾
20	ArrowMark Colorado Holdings LLC CIK 1483859 · View history	$14.14M 545,132 shares	0.26%	+545.13KNew	SEC filing ↗ Nov 14, 2025	▾

Showing 20 / 94 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

42,970,640

Not deduplicated across managers

Disclosed value

$1.11B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Maze Therapeutics, Inc. · Q3 2025

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.