Company · Ownership research

Maze Therapeutics, Inc. MAZE

CIK 0001842295 · CUSIP 578784100

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 578784100 (MAZE), not CUSIP 578784950 (MAZE), CUSIP 578784900 (MAZE), and does not merge CUSIPs.

This page lists the top 20 of 143 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$189.22M 4,567,274 shares	5.08%	0(0.00%)Unchanged	SEC filing ↗ Feb 13, 2026	▾
02	TRV GP IV, LLC CIK 1688325 · View history	$185.36M 4,473,958 shares	72.65%	-1.60M(-26.30%)Reduced	SEC filing ↗ Feb 13, 2026	▾
03	Deep Track Capital, LP CIK 1856083 · View history	$175.93M 4,246,440 shares	4.01%	+297.53K(+7.50%)Added	SEC filing ↗ Feb 13, 2026	▾
04	ARCH Venture Management, LLC CIK 1274403 · View history	$170.69M 4,120,053 shares	26.19%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
05	JANUS HENDERSON GROUP PLC CIK 1274173 · View history	$130.20M 3,142,587 shares	0.06%	+2.39M(+318.00%)Added	SEC filing ↗ Feb 17, 2026	▾
06	BlackRock, Inc. CIK 2012383 · View history	$94.76M 2,287,155 shares	0.00%	+971.14K(+73.80%)Added	SEC filing ↗ Feb 12, 2026	▾
07	a16z Capital Management, L.L.C. CIK 1540358 · View history	$70.52M 1,702,225 shares	4.46%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
08	VANGUARD GROUP INC CIK 102909 · View history	$70.31M 1,697,015 shares	0.00%	+362.06K(+27.10%)Added	SEC filing ↗ Jan 29, 2026	▾
09	VR Adviser, LLC CIK 1615982 · View history	$64.16M 1,548,569 shares	3.17%	+317.80K(+25.80%)Added	SEC filing ↗ Feb 17, 2026	▾
10	Alphabet Inc. CIK 1652044 · View history	$57.53M 1,388,583 shares	2.23%	-1.02M(-42.40%)Reduced	SEC filing ↗ Feb 13, 2026	▾
11	General Catalyst Group Management, LLC CIK 1637946 · View history	$42.92M 1,035,910 shares	19.35%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
12	Woodline Partners LP CIK 1784547 · View history	$42.89M 1,035,229 shares	0.17%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
13	TRV GP V, LLC CIK 1990717 · View history	$39.39M 950,800 shares	9.18%	0(0.00%)Unchanged	SEC filing ↗ Feb 13, 2026	▾
14	Logos Global Management LP CIK 1792126 · View history	$39.36M 950,000 shares	2.62%	-277.30K(-22.60%)Reduced	SEC filing ↗ Feb 17, 2026	▾
15	Bellevue Group AG CIK 1674546 · View history	$36.78M 887,708 shares	0.70%	+887.71KNew	SEC filing ↗ Feb 17, 2026	▾
16	MARSHALL WACE, LLP CIK 1318757 · View history	$35.11M 847,472 shares	0.03%	+69.77K(+9.00%)Added	SEC filing ↗ Feb 13, 2026	▾
17	ArrowMark Colorado Holdings LLC CIK 1483859 · View history	$31.79M 767,383 shares	0.70%	+222.25K(+40.80%)Added	SEC filing ↗ Feb 17, 2026	▾
18	Casdin Capital, LLC CIK 1534261 · View history	$31.44M 758,857 shares	1.95%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
19	FMR LLC CIK 315066 · View history	$30.19M 728,605 shares	0.00%	+72.99K(+11.10%)Added	SEC filing ↗ Feb 17, 2026	▾
20	Ikarian Capital, LLC CIK 1778253 · View history	$26.71M 644,680 shares	3.46%	-96.14K(-13.00%)Reduced	SEC filing ↗ Feb 18, 2026	▾

Showing 20 / 143 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

143

Cancelled or null records excluded

Disclosed shares

48,366,868

Not deduplicated across managers

Disclosed value

$2.00B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Maze Therapeutics, Inc. · Q4 2025

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.