Company · Ownership research

Mineralys Therapeutics, Inc. MLYS

CIK 0001933414 · CUSIP 603170101

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 603170101 (MLYS), not CUSIP 603170901 (MLYS), CUSIP 603170951 (MLYS), CUSIP SBP9N0G08 (MLYS), and does not merge CUSIPs.

This page lists the top 20 of 226 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	Catalys Pacific, LLC CIK 2011385 · View history	$213.25M 7,903,838 shares	92.94%	0(0.00%)Unchanged	SEC filing ↗ Aug 5, 2026	▾
02	RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history	$207.55M 7,692,750 shares	1.80%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾
03	BlackRock, Inc. CIK 2012383 · View history	$158.83M 5,887,038 shares	0.00%	+1.41M(+31.40%)Added	SEC filing ↗ Aug 7, 2026	▾
04	Samsara BioCapital, LLC CIK 1744967 · View history	$158.40M 5,871,018 shares	13.01%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾
05	FMR LLC CIK 315066 · View history	$121.73M 4,511,689 shares	0.01%	-349.42K(-7.20%)Reduced	SEC filing ↗ Aug 13, 2026	▾
06	STATE STREET CORP CIK 93751 · Amended · View history	$111.74M 4,141,636 shares	0.00%	+1.21M(+41.10%)Added	SEC filing ↗ Sep 22, 2026	▾
07	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) CIK 1009258 · View history	$106.79M 3,958,000 shares	1.11%	+3.96MNew	SEC filing ↗ Aug 14, 2026	▾
08	VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · View history	$74.38M 2,756,770 shares	0.00%	+302.41K(+12.30%)Added	SEC filing ↗ Aug 13, 2026	▾
09	Laurion Capital Management LP CIK 1390202 · View history	$67.62M 2,506,152 shares	4.90%	+274.11K(+12.30%)Added	SEC filing ↗ Aug 13, 2026	▾
10	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$61.04M 2,262,476 shares	0.01%	+919.16K(+68.40%)Added	SEC filing ↗ Aug 14, 2026	▾
11	ORBIMED ADVISORS LLC CIK 1055951 · View history	$56.94M 2,110,300 shares	1.08%	+57.40K(+2.80%)Added	SEC filing ↗ Aug 14, 2026	▾
12	Capital World Investors CIK 1422849 · View history	$53.90M 1,997,607 shares	0.01%	+1.60M(+401.70%)Added	SEC filing ↗ Aug 12, 2026	▾
13	ARMISTICE CAPITAL, LLC CIK 1601086 · View history	$46.84M 1,736,000 shares	1.30%	+560.00K(+47.60%)Added	SEC filing ↗ Aug 14, 2026	▾
14	Troluce Capital Advisors LLC CIK 1910321 · View history	$46.64M 1,728,753 shares	17.47%	+1.07M(+163.90%)Added	SEC filing ↗ Aug 14, 2026	▾
15	FRANKLIN RESOURCES INC CIK 38777 · View history	$44.13M 1,635,520 shares	0.01%	-149.14K(-8.40%)Reduced	SEC filing ↗ Aug 13, 2026	▾
16	ANDERA PARTNERS CIK 1757283 · View history	$42.95M 1,591,917 shares	20.80%	0(0.00%)Unchanged	SEC filing ↗ Jul 22, 2026	▾
17	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$42.75M 1,584,326 shares	0.00%	+283.19K(+21.80%)Added	SEC filing ↗ Aug 12, 2026	▾
18	SR One Capital Management, LP CIK 1910264 · View history	$42.20M 1,563,966 shares	4.06%	0(0.00%)Unchanged	SEC filing ↗ Aug 12, 2026	▾
19	BANK OF AMERICA CORP /DE/ CIK 70858 · View history	$40.62M 1,505,547 shares	0.00%	+405.18K(+36.80%)Added	SEC filing ↗ Aug 14, 2026	▾
20	SPHERA FUNDS MANAGEMENT LTD. CIK 1496201 · View history	$39.66M 1,469,971 shares	5.68%	+130.00K(+9.70%)Added	SEC filing ↗ Aug 14, 2026	▾

Showing 20 / 226 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

226

Cancelled or null records excluded

Disclosed shares

99,652,143

Not deduplicated across managers

Disclosed value

$2.69B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Mineralys Therapeutics, Inc. · Q2 2026

Explore all 226 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.