Company · Ownership research

Orchestra BioMed Holdings, Inc. OBIO

CIK 0001814114 · CUSIP 68572M106

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 68572M106 (OBIO), not CUSIP 68572M906 (OBIO), CUSIP 68572M956 (OBIO), CUSIP G4411D109 (OBIO), and does not merge CUSIPs.

This page lists the top 20 of 60 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	RTW INVESTMENTS, LP CIK 1493215 · View history	$22.26M 8,306,062 shares	0.32%	+99.90K(+1.20%)Added	SEC filing ↗ Aug 14, 2025	▾
02	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$12.31M 4,592,556 shares	0.46%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
03	VANGUARD GROUP INC CIK 102909 · View history	$3.10M 1,157,317 shares	0.00%	-150.45K(-11.50%)Reduced	SEC filing ↗ Aug 11, 2025	▾
04	BlackRock, Inc. CIK 2012383 · View history	$1.83M 681,349 shares	0.00%	-1.26M(-65.00%)Reduced	SEC filing ↗ Aug 12, 2025	▾
05	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$1.18M 438,369 shares	0.00%	-21.75K(-4.70%)Reduced	SEC filing ↗ Aug 14, 2025	▾
06	MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history	$1.10M 409,674 shares	0.00%	+409.67KNew	SEC filing ↗ Aug 14, 2025	▾
07	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$809.90K 302,082 shares	0.00%	-293.35K(-49.30%)Reduced	SEC filing ↗ Aug 8, 2025	▾
08	RENAISSANCE TECHNOLOGIES LLC CIK 1037389 · View history	$453.99K 169,400 shares	0.00%	+169.40KNew	SEC filing ↗ Aug 13, 2025	▾
09	CHARLES SCHWAB INVESTMENT MANAGEMENT INC CIK 884546 · View history	$371.42K 138,591 shares	0.00%	-78.39K(-36.10%)Reduced	SEC filing ↗ Aug 12, 2025	▾
10	STATE STREET CORP CIK 93751 · View history	$348.76K 130,133 shares	0.00%	-343.59K(-72.50%)Reduced	SEC filing ↗ Aug 14, 2025	▾
11	SUSQUEHANNA INTERNATIONAL GROUP, LLP CIK 1446194 · View history	$317.74K 118,558 shares	0.00%	+85.57K(+259.40%)Added	SEC filing ↗ Aug 14, 2025	▾
12	NORTHERN TRUST CORP CIK 73124 · View history	$269.17K 100,435 shares	0.00%	-138.27K(-57.90%)Reduced	SEC filing ↗ Aug 13, 2025	▾
13	Knott David M Jr CIK 1892770 · View history	$268.00K 100,000 shares	0.12%	+100.00KNew	SEC filing ↗ Aug 11, 2025	▾
14	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$259.53K 96,841 shares	0.00%	+48.11K(+98.70%)Added	SEC filing ↗ Aug 14, 2025	▾
15	TD Asset Management Inc CIK 1056053 · View history	$248.38K 92,678 shares	0.00%	0(0.00%)Unchanged	SEC filing ↗ Jul 28, 2025	▾
16	IFP Advisors, Inc CIK 1641866 · View history	$228.76K 85,358 shares	0.01%	-76.56K(-47.30%)Reduced	SEC filing ↗ Jul 24, 2025	▾
17	HighTower Advisors, LLC CIK 1462245 · View history	$178.22K 66,500 shares	0.00%	+5.50K(+9.00%)Added	SEC filing ↗ Aug 11, 2025	▾
18	Knoll Capital Management, LLC CIK 1325083 · View history	$169.82K 455,128 shares	0.12%	+455.13KNew	SEC filing ↗ Aug 14, 2025	▾
19	LASRY MARC CIK 1259927 · View history	$163.13K 60,869 shares	0.91%	0(0.00%)Unchanged	SEC filing ↗ Aug 15, 2025	▾
20	Holos Integrated Wealth LLC CIK 2080096 · View history	$139.82K 51,595 shares	0.08%	0(0.00%)Unchanged	SEC filing ↗ Aug 13, 2025	▾

Showing 20 / 60 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

18,134,641

Not deduplicated across managers

Disclosed value

$47.55M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Orchestra BioMed Holdings, Inc. · Q2 2025

Explore all 60 reporting institutions.

This page includes 20 of 60 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

Download CSV
Earlier quarters
Advanced screening & filtering
API & AI access

Already have an account?

＋ New accounts get free API credits to explore data beyond ownership filings.

For AI agents & developers

The initial HTML of this page carries its exact data as script#research-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 20 of 60 reporting institutions; totals use the complete disclosed data.

Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP / CLI.

MCP  https://api.akkrudata.ai/mcp

akkru_institutional_holdings
{"action":"holders","cusip":"68572M106","quarter":"2025Q2","type":"positions","page_size":100}

Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.

MCP endpoint: https://api.akkrudata.ai/mcp
API / MCP / CLI documentation: /documents
llms.txt: /llms.txt

Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.