PERCEPTIVE ADVISORS LLC
CIK 1224962 · Holdings on Jun 30, 2025 · First reported Aug 14, 2025
Top ten holdings
Q2 2025- VRNA19.55%
- ASND6.24%
- ACLX6.12%
- RYTM5.73%
- NUVL3.94%
- AORT3.26%
- MGTX3.09%
- INSM2.46%
- EWTX2.28%
- PTGX2.23%
Share classes counted separately54.90%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- VRNAWeight increased · +4.77 pp14.78% → 19.55%Shares -1.06M (-16.09%)
- 03152W109Weight decreased · -4.62 pp6.21% → 1.59%Shares -14.05M (-65.46%)
- EWTXWeight decreased · -2.83 pp5.11% → 2.28%Shares -1.91M (-29.13%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 27
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | VRNAVERONA PHARMA PLC - ADRSPONSORED ADS View history and evidence | $520.91M | 19.55% | 5.51M shares | 14.78% → 19.55%+4.77 pp -1.06M (-16.09%) | Reduced | ↗▾ |
| 02 | ASNDASCENDIS PHARMA A/SSPONSORED ADR View history and evidence | $166.37M | 6.24% | 963.89K shares | Prior unavailable +963.89K | New | ↗▾ |
| 03 | ACLXARCELLX INCCOMMON STOCK View history and evidence | $163.18M | 6.12% | 2.48M shares | 6.81% → 6.12%-0.69 pp -448.48K (-15.32%) | Reduced | ↗▾ |
| 04 | RYTMRHYTHM PHARMACEUTICALS INC View history and evidence | $152.81M | 5.73% | 2.42M shares | 4.79% → 5.73%+0.94 pp -130.15K (-5.11%) | Reduced | ↗▾ |
| 05 | NUVLNUVALENT INC-A View history and evidence | $104.93M | 3.94% | 1.38M shares | 4.11% → 3.94%-0.17 pp -258.79K (-15.84%) | Reduced | ↗▾ |
| 06 | AORTARTIVION INC View history and evidence | $86.88M | 3.26% | 2.79M shares | 2.44% → 3.26%+0.82 pp 0 (0.00%) | Unchanged | ↗▾ |
| 07 | MGTXMEIRAGTX HOLDINGS PLC View history and evidence | $82.23M | 3.09% | 12.63M shares | 3.02% → 3.09%+0.07 pp +45.00K (+0.36%) | Added | ↗▾ |
| 08 | INSMINSMED INCCOM PAR $.01 View history and evidence | $65.44M | 2.46% | 650.25K shares | 1.38% → 2.46%+1.08 pp +140.95K (+27.68%) | Added | ↗▾ |
| 09 | EWTXEDGEWISE THERAPEUTICS INC View history and evidence | $60.83M | 2.28% | 4.64M shares | 5.11% → 2.28%-2.83 pp -1.91M (-29.13%) | Reduced | ↗▾ |
| 10 | PTGXPROTAGONIST THERAPEUTICS INC View history and evidence | $59.38M | 2.23% | 1.07M shares | 1.87% → 2.23%+0.36 pp -16.82K (-1.54%) | Reduced | ↗▾ |
Options overlay 3
$32.33M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
XBISS SPDR S&P BIOTECH ETFS&P BIOTECH View history and evidence | Put | 300.00K | $24.88M | +300.00K | ▾ |
CAPRCAPRICOR THERAPEUTICS INCCOM NEW View history and evidence | Put | 650.00K | $6.45M | +650.00K | ▾ |
CAPRCAPRICOR THERAPEUTICS INCCOM NEW View history and evidence | Call | 100.00K | $993.00K | +100.00K | ▾ |
3 / 3 options · preview only
Exited positions 22
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| ITCI INTRA-CELLULAR THERAPIES INC | Non-derivative | -786,358 | -$103.74M | SEC filing ↗ | SEC filing ↗ |
| IOVA IOVANCE BIOTHERAPEUTICS INC | Non-derivative | -12,711,788 | -$42.33M | SEC filing ↗ | SEC filing ↗ |
| ARGX ARGENX SE - ADR | Non-derivative | -59,510 | -$35.22M | SEC filing ↗ | SEC filing ↗ |
3 / 22 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1224962 · Period 2025-06-30
Data loaded 2026-09-23 · First reported 2025-08-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 2697358275
}Research all 85 reported holdings.
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