PERCEPTIVE ADVISORS LLC
CIK 1224962 · Holdings on Mar 31, 2025 · First reported Aug 6, 2025
Top ten holdings
Q1 2025- VRNA14.78%
- ACLX6.81%
- 03152W1096.21%
- EWTX5.11%
- RYTM4.79%
- NUVL4.11%
- SLNO3.82%
- ITCI3.68%
- MGTX3.02%
- AORT2.44%
Share classes counted separately54.77%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- VRNAWeight increased · +6.51 pp8.27% → 14.78%Shares +171.23K (+2.68%)
- EWTXWeight increased · +3.11 pp2.00% → 5.11%Shares +3.86M (+143.80%)
- IOVAWeight decreased · -3.06 pp4.56% → 1.50%Shares -9.40M (-42.51%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 29
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | VRNAVERONA PHARMA PLC - ADRSPONSORED ADS View history and evidence | $416.71M | 14.78% | 6.56M shares | 8.27% → 14.78%+6.51 pp +171.23K (+2.68%) | Added | ↗▾ |
| 02 | ACLXARCELLX INCCOMMON STOCK View history and evidence | $191.98M | 6.81% | 2.93M shares | 7.43% → 6.81%-0.62 pp -552.41K (-15.88%) | Reduced | ↗▾ |
| 03 | 03152W109AMICUS THERAPEUTICS INC View history and evidence | $175.15M | 6.21% | 21.46M shares | 6.36% → 6.21%-0.15 pp -2.78M (-11.47%) | Reduced | ↗▾ |
| 04 | EWTXEDGEWISE THERAPEUTICS INC View history and evidence | $144.04M | 5.11% | 6.55M shares | 2.00% → 5.11%+3.11 pp +3.86M (+143.80%) | Added | ↗▾ |
| 05 | RYTMRHYTHM PHARMACEUTICALS INC View history and evidence | $134.99M | 4.79% | 2.55M shares | 5.74% → 4.79%-0.95 pp -1.13M (-30.76%) | Reduced | ↗▾ |
| 06 | NUVLNUVALENT INC-A View history and evidence | $115.88M | 4.11% | 1.63M shares | 5.71% → 4.11%-1.60 pp -986.01K (-37.63%) | Reduced | ↗▾ |
| 07 | SLNOSOLENO THERAPEUTICS INC View history and evidence | $107.65M | 3.82% | 1.51M shares | 1.88% → 3.82%+1.94 pp +5.56K (+0.37%) | Added | ↗▾ |
| 08 | ITCIINTRA-CELLULAR THERAPIES INC View history and evidence | $103.74M | 3.68% | 786.36K shares | 3.00% → 3.68%+0.68 pp -501.97K (-38.96%) | Reduced | ↗▾ |
| 09 | MGTXMEIRAGTX HOLDINGS PLC View history and evidence | $85.25M | 3.02% | 12.58M shares | 2.13% → 3.02%+0.89 pp 0 (0.00%) | Unchanged | ↗▾ |
| 10 | AORTARTIVION INC View history and evidence | $68.67M | 2.44% | 2.79M shares | 2.23% → 2.44%+0.21 pp 0 (0.00%) | Unchanged | ↗▾ |
Options overlay 1
$11.00M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
EWTXEDGEWISE THERAPEUTICS INC View history and evidence | Call | 500.00K | $11.00M | +500.00K | ▾ |
1 / 1 options · preview only
Exited positions 28
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| PRAX PRAXIS PRECISION MEDICINES I | Call | -500,000 | -$38.48M | SEC filing ↗ | SEC filing ↗ |
| PRCT PROCEPT BIOROBOTICS CORP | Non-derivative | -290,659 | -$23.40M | SEC filing ↗ | SEC filing ↗ |
| NTRA NATERA INC | Non-derivative | -125,000 | -$19.79M | SEC filing ↗ | SEC filing ↗ |
3 / 28 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1224962 · Period 2025-03-31
Data loaded 2026-09-23 · First reported 2025-08-06
Amendments and versions
{
"amendments_merged": [
{
"action": "REPLACE",
"accession": "0001012975-25-000422",
"cover_total": 2830733555,
"filing_date": "2025-08-06",
"claimed_type": "RESTATEMENT",
"confidential": false,
"positions_added": 0,
"positions_restated": 1,
"positions_cancelled": 0
}
],
"prior_versions": [
{
"accession": "0001012975-25-000242",
"filing_date": "2025-05-15",
"confidential": false,
"cover_table_value_total_raw": 2838202794
}
],
"cover_table_value": 2830733555
}Research all 87 reported holdings.
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