PERCEPTIVE ADVISORS LLC
CIK 1224962 · Holdings on Mar 31, 2026 · First reported May 29, 2026
Top ten holdings
Q1 2026- PRAX12.96%
- CELC7.05%
- ASND6.92%
- ROIV4.53%
- CNTA4.13%
- RYTM4.08%
- SYRE3.77%
- NUVL3.20%
- EWTX2.75%
- PTGX2.56%
Share classes counted separately51.95%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- CNTAWeight increased · +2.79 pp1.34% → 4.13%Shares +2.34M (+80.25%)
- ASNDWeight increased · +2.70 pp4.22% → 6.92%Shares +450.00K (+41.61%)
- PRAXWeight increased · +2.18 pp10.78% → 12.96%Shares +40.00K (+2.00%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 28
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | PRAXPRAXIS PRECISION MEDICINES ICOM NEW View history and evidence | $655.97M | 12.96% | 2.04M shares | 10.78% → 12.96%+2.18 pp +40.00K (+2.00%) | Added | ↗▾ |
| 02 | CELCCELCUITY INC View history and evidence | $356.94M | 7.05% | 3.13M shares | 5.77% → 7.05%+1.28 pp -33.00K (-1.04%) | Reduced | ↗▾ |
| 03 | ASNDASCENDIS PHARMA A/SSPONSORED ADR View history and evidence | $350.28M | 6.92% | 1.53M shares | 4.22% → 6.92%+2.70 pp +450.00K (+41.61%) | Added | ↗▾ |
| 04 | ROIVROIVANT SCIENCES LTDSHS View history and evidence | $229.51M | 4.53% | 8.29M shares | 3.17% → 4.53%+1.36 pp +300.00K (+3.76%) | Added | ↗▾ |
| 05 | CNTACENTESSA PHARMACEUTICALS-ADRSPONSORED ADS View history and evidence | $208.88M | 4.13% | 5.26M shares | 1.34% → 4.13%+2.79 pp +2.34M (+80.25%) | Added | ↗▾ |
| 06 | RYTMRHYTHM PHARMACEUTICALS INC View history and evidence | $206.45M | 4.08% | 2.37M shares | 4.99% → 4.08%-0.91 pp -172.60K (-6.78%) | Reduced | ↗▾ |
| 07 | SYRESPYRE THERAPEUTICS INCCOM NEW View history and evidence | $190.83M | 3.77% | 3.78M shares | 1.84% → 3.77%+1.93 pp +714.00K (+23.26%) | Added | ↗▾ |
| 08 | NUVLNUVALENT INC-A View history and evidence | $161.92M | 3.20% | 1.58M shares | 3.07% → 3.20%+0.13 pp -84.60K (-5.08%) | Reduced | ↗▾ |
| 09 | EWTXEDGEWISE THERAPEUTICS INC View history and evidence | $139.36M | 2.75% | 4.42M shares | 2.03% → 2.75%+0.72 pp -34.00K (-0.76%) | Reduced | ↗▾ |
| 10 | PTGXPROTAGONIST THERAPEUTICS INC View history and evidence | $129.73M | 2.56% | 1.23M shares | 2.16% → 2.56%+0.40 pp -119.55K (-8.85%) | Reduced | ↗▾ |
Options overlay 2
$55.03M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
MRNAMODERNA INC View history and evidence | Put | 1.00M | $50.80M | +1.00M | ▾ |
OCULOCULAR THERAPEUTIX INC View history and evidence | Call | 500.00K | $4.24M | +500.00K | ▾ |
2 / 2 options · preview only
Exited positions 42
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| XBI SS SPDR S&P BIOTECH ETF | Put | -1,100,000 | -$134.12M | SEC filing ↗ | SEC filing ↗ |
| EXK EXACT SCIENCES CORP | Non-derivative | -1,200,487 | -$121.92M | SEC filing ↗ | SEC filing ↗ |
| ACLX ARCELLX INC | Non-derivative | -1,466,071 | -$95.59M | SEC filing ↗ | SEC filing ↗ |
3 / 42 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1224962 · Period 2026-03-31
Data loaded 2026-09-23 · First reported 2026-05-29
Amendments and versions
{
"amendments_merged": [
{
"action": "REPLACE",
"accession": "0001012975-26-000499",
"cover_total": 5117574591,
"filing_date": "2026-05-29",
"claimed_type": "RESTATEMENT",
"confidential": false,
"positions_added": 0,
"positions_restated": 1,
"positions_cancelled": 0
}
],
"prior_versions": [
{
"accession": "0001012975-26-000443",
"filing_date": "2026-05-15",
"confidential": false,
"cover_table_value_total_raw": 5110910164
}
],
"cover_table_value": 5117574591
}Research all 94 reported holdings.
This page includes 30 of 94 reported holdings. Sign in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.
- Download CSV
- Earlier quarters
- Advanced screening & filtering
- API & AI access
＋ New accounts get free API credits to explore data beyond ownership filings.
For AI agents & developers
The initial HTML of this page carries its exact data as script#portfolio-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 30 of 94 current positions (options included); totals and weights use the complete filing.
Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP.
MCP https://api.akkrudata.ai/mcp
get_institutional_portfolio
{"cik":"1224962","quarter":"2026Q1","page_size":100}
get_institutional_manager_history
{"cik":"1224962","page_size":100}Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.
- MCP endpoint
- https://api.akkrudata.ai/mcp
- API / MCP documentation
- /documents
- llms.txt
- /llms.txt
Sources, coverage & how to read this data
Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.