Company · Ownership research

Protagonist Therapeutics, Inc PTGX

CIK 0001377121 · CUSIP 74366E102

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 74366E102 (PTGX), not CUSIP 74366E902 (PTGX), CUSIP 74366E952 (PTGX), CUSIP 074366E10 (PTGX), and does not merge CUSIPs.

This page lists the top 20 of 317 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	BlackRock, Inc. CIK 2012383 · View history	$848.60M 9,715,999 shares	0.01%	+311.77K(+3.30%)Added	SEC filing ↗ Feb 12, 2026	▾
02	FARALLON CAPITAL MANAGEMENT LLC CIK 909661 · Amended · View history	$536.62M 6,144,006 shares	2.79%	-52.00K(-0.80%)Reduced	SEC filing ↗ Feb 17, 2026	▾
03	VANGUARD GROUP INC CIK 102909 · View history	$472.83M 5,413,690 shares	0.01%	+1.16M(+27.20%)Added	SEC filing ↗ Jan 29, 2026	▾
04	RTW INVESTMENTS, LP CIK 1493215 · View history	$441.86M 5,059,053 shares	4.43%	-697.22K(-12.10%)Reduced	SEC filing ↗ Feb 17, 2026	▾
05	STATE STREET CORP CIK 93751 · View history	$279.46M 3,199,729 shares	0.01%	+33.93K(+1.10%)Added	SEC filing ↗ Feb 13, 2026	▾
06	WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history	$276.99M 3,171,423 shares	0.05%	+1.26M(+66.20%)Added	SEC filing ↗ Feb 17, 2026	▾
07	UBS Group AG CIK 1610520 · View history	$241.93M 2,770,021 shares	0.05%	+874.01K(+46.10%)Added	SEC filing ↗ Jan 29, 2026	▾
08	JANUS HENDERSON GROUP PLC CIK 1274173 · View history	$231.35M 2,649,981 shares	0.10%	+1.55M(+140.70%)Added	SEC filing ↗ Feb 17, 2026	▾
09	JOHNSON & JOHNSON CIK 200406 · Amended · View history	$213.91M 2,449,183 shares	38.54%	0(0.00%)Unchanged	SEC filing ↗ Mar 18, 2026	▾
10	Invesco Ltd. CIK 914208 · Amended · View history	$136.94M 1,567,840 shares	0.01%	+564.13K(+56.20%)Added	SEC filing ↗ Feb 19, 2026	▾
11	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$126.92M 1,452,928 shares	0.01%	+36.28K(+2.60%)Added	SEC filing ↗ Feb 9, 2026	▾
12	Woodline Partners LP CIK 1784547 · View history	$123.04M 1,408,772 shares	0.48%	-29.48K(-2.00%)Reduced	SEC filing ↗ Feb 17, 2026	▾
13	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$122.34M 1,400,738 shares	0.01%	+180.30K(+14.80%)Added	SEC filing ↗ Feb 17, 2026	▾
14	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$117.95M 1,350,425 shares	2.16%	+320.29K(+31.10%)Added	SEC filing ↗ Feb 17, 2026	▾
15	CITADEL ADVISORS LLC CIK 1423053 · View history	$98.40M 1,126,687 shares	0.07%	+888.81K(+373.60%)Added	SEC filing ↗ Feb 17, 2026	▾
16	Driehaus Capital Management LLC CIK 938206 · View history	$96.00M 1,099,170 shares	0.65%	-40.68K(-3.60%)Reduced	SEC filing ↗ Feb 17, 2026	▾
17	ADAR1 Capital Management, LLC CIK 1940272 · Amended · View history	$91.63M 1,049,168 shares	6.85%	+59.99K(+6.10%)Added	SEC filing ↗ Feb 18, 2026	▾
18	MARSHALL WACE, LLP CIK 1318757 · View history	$89.52M 1,024,925 shares	0.09%	-60.64K(-5.60%)Reduced	SEC filing ↗ Feb 13, 2026	▾
19	GOLDMAN SACHS GROUP INC CIK 886982 · Amended · View history	$83.95M 961,149 shares	0.01%	+179.44K(+23.00%)Added	SEC filing ↗ Mar 25, 2026	▾
20	MORGAN STANLEY CIK 895421 · Amended · View history	$76.77M 879,024 shares	0.00%	+110.67K(+14.40%)Added	SEC filing ↗ May 27, 2026	▾

Showing 20 / 317 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

317

Cancelled or null records excluded

Disclosed shares

71,028,771

Not deduplicated across managers

Disclosed value

$6.18B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Protagonist Therapeutics, Inc · Q4 2025

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.