Company · Ownership research

Protagonist Therapeutics, Inc PTGX

CIK 0001377121 · CUSIP 74366E102

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 74366E102 (PTGX), not CUSIP 74366E902 (PTGX), CUSIP 74366E952 (PTGX), CUSIP 074366E10 (PTGX), and does not merge CUSIPs.

This page lists the top 20 of 276 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	BlackRock, Inc. CIK 2012383 · View history	$624.72M 9,404,232 shares	0.01%	-226.11K(-2.30%)Reduced	SEC filing ↗ Nov 12, 2025	▾
02	FARALLON CAPITAL MANAGEMENT LLC CIK 909661 · Amended · View history	$411.60M 6,196,006 shares	2.33%	+24.00K(+0.40%)Added	SEC filing ↗ Feb 17, 2026	▾
03	RTW INVESTMENTS, LP CIK 1493215 · View history	$382.39M 5,756,277 shares	4.71%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
04	VANGUARD GROUP INC CIK 102909 · View history	$282.81M 4,257,229 shares	0.00%	-101.37K(-2.30%)Reduced	SEC filing ↗ Nov 7, 2025	▾
05	STATE STREET CORP CIK 93751 · View history	$210.30M 3,165,795 shares	0.01%	-41.75K(-1.30%)Reduced	SEC filing ↗ Nov 14, 2025	▾
06	BVF INC/IL CIK 1056807 · View history	$170.12M 2,560,916 shares	6.90%	-650.13K(-20.20%)Reduced	SEC filing ↗ Nov 14, 2025	▾
07	JOHNSON & JOHNSON CIK 200406 · Amended · View history	$162.70M 2,449,183 shares	32.29%	0(0.00%)Unchanged	SEC filing ↗ Mar 18, 2026	▾
08	WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history	$126.78M 1,908,446 shares	0.02%	+870.71K(+83.90%)Added	SEC filing ↗ Nov 14, 2025	▾
09	UBS Group AG CIK 1610520 · View history	$125.95M 1,896,008 shares	0.02%	-605.24K(-24.20%)Reduced	SEC filing ↗ Nov 13, 2025	▾
10	Deep Track Capital, LP CIK 1856083 · View history	$113.97M 1,715,691 shares	3.18%	-1.53M(-47.10%)Reduced	SEC filing ↗ Nov 14, 2025	▾
11	Woodline Partners LP CIK 1784547 · View history	$95.54M 1,438,247 shares	0.45%	+491.36K(+51.90%)Added	SEC filing ↗ Nov 14, 2025	▾
12	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$94.12M 1,416,646 shares	0.01%	-27.58K(-1.90%)Reduced	SEC filing ↗ Nov 12, 2025	▾
13	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$81.08M 1,220,436 shares	0.01%	+283.73K(+30.30%)Added	SEC filing ↗ Nov 14, 2025	▾
14	Driehaus Capital Management LLC CIK 938206 · View history	$75.72M 1,139,854 shares	0.54%	+382.14K(+50.40%)Added	SEC filing ↗ Nov 14, 2025	▾
15	JANUS HENDERSON GROUP PLC CIK 1274173 · View history	$73.17M 1,100,821 shares	0.03%	+653.99K(+146.40%)Added	SEC filing ↗ Nov 14, 2025	▾
16	MARSHALL WACE, LLP CIK 1318757 · View history	$72.11M 1,085,564 shares	0.08%	+1.09MNew	SEC filing ↗ Nov 13, 2025	▾
17	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$68.43M 1,030,134 shares	1.98%	-44.31K(-4.10%)Reduced	SEC filing ↗ Nov 14, 2025	▾
18	COMMODORE CAPITAL LP CIK 1831942 · View history	$68.09M 1,025,000 shares	3.32%	-50.00K(-4.70%)Reduced	SEC filing ↗ Nov 14, 2025	▾
19	Invesco Ltd. CIK 914208 · View history	$66.68M 1,003,706 shares	0.01%	+282.03K(+39.10%)Added	SEC filing ↗ Nov 13, 2025	▾
20	ADAR1 Capital Management, LLC CIK 1940272 · View history	$65.71M 989,182 shares	6.51%	+41.11K(+4.30%)Added	SEC filing ↗ Nov 14, 2025	▾

Showing 20 / 276 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

276

Cancelled or null records excluded

Disclosed shares

70,684,522

Not deduplicated across managers

Disclosed value

$4.70B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Protagonist Therapeutics, Inc · Q3 2025

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.