Company · Ownership research

Design Therapeutics, Inc. DSGN

CIK 0001807120 · CUSIP 25056L103

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 25056L103 (DSGN), not CUSIP 25056L903 (DSGN), CUSIP 25056L953 (DSGN), and does not merge CUSIPs.

This page lists the top 20 of 95 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	SR One Capital Management, LP CIK 1910264 · View history	$49.14M 6,526,476 shares	7.11%	0(0.00%)Unchanged	SEC filing ↗ Nov 12, 2025	▾
02	Logos Global Management LP CIK 1792126 · View history	$27.52M 3,655,000 shares	2.72%	-562.63K(-13.30%)Reduced	SEC filing ↗ Nov 14, 2025	▾
03	Point72 Asset Management, L.P. CIK 1603466 · View history	$25.15M 3,340,552 shares	0.05%	+1.53M(+84.80%)Added	SEC filing ↗ Nov 14, 2025	▾
04	BlackRock, Inc. CIK 2012383 · View history	$15.39M 2,044,388 shares	0.00%	-351.36K(-14.70%)Reduced	SEC filing ↗ Nov 12, 2025	▾
05	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$14.71M 1,953,547 shares	0.44%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
06	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$13.41M 1,780,975 shares	0.52%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
07	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$12.90M 1,712,882 shares	0.09%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
08	Almitas Capital LLC CIK 1596468 · Amended · View history	$11.52M 1,530,435 shares	2.64%	0(0.00%)Unchanged	SEC filing ↗ Nov 17, 2025	▾
09	VANGUARD GROUP INC CIK 102909 · View history	$10.87M 1,443,701 shares	0.00%	-27.87K(-1.90%)Reduced	SEC filing ↗ Nov 7, 2025	▾
10	Driehaus Capital Management LLC CIK 938206 · View history	$8.10M 1,076,236 shares	0.06%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
11	Kynam Capital Management, LP CIK 1907884 · View history	$7.75M 1,029,579 shares	0.58%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
12	FMR LLC CIK 315066 · View history	$5.58M 740,849 shares	0.00%	-210.35K(-22.10%)Reduced	SEC filing ↗ Nov 13, 2025	▾
13	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$5.24M 695,613 shares	0.00%	-98.39K(-12.40%)Reduced	SEC filing ↗ Nov 12, 2025	▾
14	STATE STREET CORP CIK 93751 · View history	$4.78M 634,397 shares	0.00%	-84.81K(-11.80%)Reduced	SEC filing ↗ Nov 14, 2025	▾
15	ACADIAN ASSET MANAGEMENT LLC CIK 916542 · View history	$4.65M 617,489 shares	0.01%	-9.86K(-1.60%)Reduced	SEC filing ↗ Nov 13, 2025	▾
16	Woodline Partners LP CIK 1784547 · View history	$4.61M 612,712 shares	0.02%	-164.82K(-21.20%)Reduced	SEC filing ↗ Nov 14, 2025	▾
17	MPM BIOIMPACT LLC CIK 1687078 · View history	$4.18M 555,187 shares	0.68%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
18	CITADEL ADVISORS LLC CIK 1423053 · View history	$4.17M 554,020 shares	0.00%	-286.77K(-34.10%)Reduced	SEC filing ↗ Nov 14, 2025	▾
19	RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history	$3.58M 475,699 shares	0.04%	+475.70KNew	SEC filing ↗ Nov 14, 2025	▾
20	D. E. Shaw & Co., Inc. CIK 1009207 · View history	$2.81M 373,276 shares	0.00%	-17.37K(-4.40%)Reduced	SEC filing ↗ Nov 14, 2025	▾

Showing 20 / 95 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

34,492,576

Not deduplicated across managers

Disclosed value

$259.73M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Design Therapeutics, Inc. · Q3 2025

Explore all 95 reporting institutions.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.