Company · Ownership research

Design Therapeutics, Inc. DSGN

CIK 0001807120 · CUSIP 25056L103

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 25056L103 (DSGN), not CUSIP 25056L903 (DSGN), CUSIP 25056L953 (DSGN), and does not merge CUSIPs.

This page lists the top 20 of 125 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	SR One Capital Management, LP CIK 1910264 · View history	$69.44M 6,526,476 shares	7.59%	0(0.00%)Unchanged	SEC filing ↗ May 14, 2026	▾
02	RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history	$31.63M 2,972,973 shares	0.34%	+1.51M(+103.40%)Added	SEC filing ↗ May 15, 2026	▾
03	Point72 Asset Management, L.P. CIK 1603466 · View history	$28.97M 2,722,754 shares	0.05%	-2.65M(-49.30%)Reduced	SEC filing ↗ May 15, 2026	▾
04	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$27.51M 2,585,978 shares	0.16%	+352.88K(+15.80%)Added	SEC filing ↗ May 15, 2026	▾
05	BlackRock, Inc. CIK 2012383 · View history	$22.70M 2,133,764 shares	0.00%	+16.61K(+0.80%)Added	SEC filing ↗ May 13, 2026	▾
06	Logos Global Management LP CIK 1792126 · View history	$20.75M 1,950,000 shares	1.07%	-550.00K(-22.00%)Reduced	SEC filing ↗ May 15, 2026	▾
07	Driehaus Capital Management LLC CIK 938206 · View history	$18.57M 1,744,987 shares	0.14%	+565.17K(+47.90%)Added	SEC filing ↗ May 15, 2026	▾
08	Vivo Capital, LLC CIK 1674712 · Amended · View history	$17.16M 1,612,903 shares	1.43%	0(0.00%)Unchanged	SEC filing ↗ May 20, 2026	▾
09	Almitas Capital LLC CIK 1596468 · View history	$16.28M 1,530,335 shares	3.68%	-100(0.00%)Reduced	SEC filing ↗ May 15, 2026	▾
10	VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · Amended · View history	$14.36M 1,349,850 shares	0.00%	—	SEC filing ↗ May 15, 2026	▾
11	Woodline Partners LP CIK 1784547 · Amended · View history	$10.23M 961,501 shares	0.04%	+17.46K(+1.80%)Added	SEC filing ↗ May 15, 2026	▾
12	Trails Edge Capital Partners, LP CIK 2077247 · View history	$9.07M 852,013 shares	2.13%	+852.01KNew	SEC filing ↗ May 15, 2026	▾
13	FMR LLC CIK 315066 · View history	$8.50M 798,411 shares	0.00%	+27.14K(+3.50%)Added	SEC filing ↗ May 15, 2026	▾
14	Kynam Capital Management, LP CIK 1907884 · View history	$8.35M 784,606 shares	0.53%	0(0.00%)Unchanged	SEC filing ↗ May 15, 2026	▾
15	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$7.37M 692,518 shares	0.00%	+12.93K(+1.90%)Added	SEC filing ↗ May 15, 2026	▾
16	STATE STREET CORP CIK 93751 · View history	$7.02M 659,575 shares	0.00%	+11.94K(+1.80%)Added	SEC filing ↗ May 15, 2026	▾
17	MORGAN STANLEY CIK 895421 · View history	$6.99M 656,565 shares	0.00%	-45.74K(-6.50%)Reduced	SEC filing ↗ May 15, 2026	▾
18	ACADIAN ASSET MANAGEMENT LLC CIK 916542 · View history	$6.55M 616,481 shares	0.01%	+3.71K(+0.60%)Added	SEC filing ↗ May 13, 2026	▾
19	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$5.37M 504,718 shares	0.00%	+234.06K(+86.50%)Added	SEC filing ↗ May 15, 2026	▾
20	D. E. Shaw & Co., Inc. CIK 1009207 · View history	$5.00M 470,270 shares	0.00%	+31.38K(+7.10%)Added	SEC filing ↗ May 15, 2026	▾

Showing 20 / 125 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

125

Cancelled or null records excluded

Disclosed shares

37,986,626

Not deduplicated across managers

Disclosed value

$404.11M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Design Therapeutics, Inc. · Q1 2026

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.