Company · Ownership research

Design Therapeutics, Inc. DSGN

CIK 0001807120 · CUSIP 25056L103

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 25056L103 (DSGN), not CUSIP 25056L903 (DSGN), CUSIP 25056L953 (DSGN), and does not merge CUSIPs.

This page lists the top 20 of 117 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	SR One Capital Management, LP CIK 1910264 · View history	$61.22M 6,526,476 shares	8.67%	0(0.00%)Unchanged	SEC filing ↗ Feb 12, 2026	▾
02	Point72 Asset Management, L.P. CIK 1603466 · View history	$50.39M 5,372,004 shares	0.08%	+2.03M(+60.80%)Added	SEC filing ↗ Feb 17, 2026	▾
03	Logos Global Management LP CIK 1792126 · View history	$23.45M 2,500,000 shares	1.56%	-1.16M(-31.60%)Reduced	SEC filing ↗ Feb 17, 2026	▾
04	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$20.95M 2,233,099 shares	0.12%	+520.22K(+30.40%)Added	SEC filing ↗ Feb 17, 2026	▾
05	BlackRock, Inc. CIK 2012383 · View history	$19.86M 2,117,156 shares	0.00%	+72.77K(+3.60%)Added	SEC filing ↗ Feb 12, 2026	▾
06	VANGUARD GROUP INC CIK 102909 · View history	$15.30M 1,630,910 shares	0.00%	+187.21K(+13.00%)Added	SEC filing ↗ Jan 29, 2026	▾
07	Vivo Capital, LLC CIK 1674712 · View history	$15.13M 1,612,903 shares	0.98%	+1.61MNew	SEC filing ↗ Feb 13, 2026	▾
08	Almitas Capital LLC CIK 1596468 · View history	$14.36M 1,530,435 shares	3.16%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
09	RA CAPITAL MANAGEMENT, L.P. CIK 1346824 · View history	$13.71M 1,461,381 shares	0.14%	+985.68K(+207.20%)Added	SEC filing ↗ Feb 17, 2026	▾
10	Driehaus Capital Management LLC CIK 938206 · View history	$11.07M 1,179,817 shares	0.08%	+103.58K(+9.60%)Added	SEC filing ↗ Feb 17, 2026	▾
11	Woodline Partners LP CIK 1784547 · View history	$8.86M 944,039 shares	0.03%	+331.33K(+54.10%)Added	SEC filing ↗ Feb 17, 2026	▾
12	Kynam Capital Management, LP CIK 1907884 · View history	$7.36M 784,606 shares	0.48%	-244.97K(-23.80%)Reduced	SEC filing ↗ Feb 17, 2026	▾
13	FMR LLC CIK 315066 · View history	$7.23M 771,268 shares	0.00%	+30.42K(+4.10%)Added	SEC filing ↗ Feb 17, 2026	▾
14	MORGAN STANLEY CIK 895421 · Amended · View history	$6.59M 702,306 shares	0.00%	+526.32K(+299.10%)Added	SEC filing ↗ May 27, 2026	▾
15	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$6.38M 679,590 shares	0.00%	-16.02K(-2.30%)Reduced	SEC filing ↗ Feb 9, 2026	▾
16	STATE STREET CORP CIK 93751 · View history	$6.07M 647,636 shares	0.00%	+13.24K(+2.10%)Added	SEC filing ↗ Feb 13, 2026	▾
17	ACADIAN ASSET MANAGEMENT LLC CIK 916542 · View history	$5.74M 612,768 shares	0.01%	-4.72K(-0.80%)Reduced	SEC filing ↗ Feb 10, 2026	▾
18	Frazier Life Sciences Management, L.P. CIK 1892134 · View history	$4.89M 521,000 shares	0.13%	-1.43M(-73.30%)Reduced	SEC filing ↗ Feb 13, 2026	▾
19	CITADEL ADVISORS LLC CIK 1423053 · View history	$4.31M 459,874 shares	0.00%	-94.15K(-17.00%)Reduced	SEC filing ↗ Feb 17, 2026	▾
20	D. E. Shaw & Co., Inc. CIK 1009207 · View history	$4.12M 438,894 shares	0.00%	+65.62K(+17.60%)Added	SEC filing ↗ Feb 17, 2026	▾

Showing 20 / 117 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

117

Cancelled or null records excluded

Disclosed shares

38,119,032

Not deduplicated across managers

Disclosed value

$357.55M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Design Therapeutics, Inc. · Q4 2025

Explore all 117 reporting institutions.

This page includes 20 of 117 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.