IONIS PHARMACEUTICALS INC IONS
CIK 0000874015 · CUSIP 462222100
Quarter-end disclosures, not live holdings.
Top 20 institutions
Weight means this stock's share of the manager's own portfolio.
| # | Manager | Value | Manager weight | Change vs prior | Source | |
|---|---|---|---|---|---|---|
| 01 | FMR LLC CIK 315066 · View history | $1.95B 24,631,956 shares | 0.08% | +75.32K(+0.3%)Added | SEC filing ↗ Aug 13, 2026 | ▾ |
| 02 | Capital World Investors CIK 1422849 · View history | $1.72B 21,669,226 shares | 0.20% | +482.86K(+2.3%)Added | SEC filing ↗ Aug 12, 2026 | ▾ |
| 03 | BlackRock, Inc. CIK 2012383 · View history | $848.77M 10,704,660 shares | 0.01% | +262.18K(+2.5%)Added | SEC filing ↗ Aug 7, 2026 | ▾ |
| 04 | VANGUARD PORTFOLIO MANAGEMENT LLC CIK 2100121 · View history | $623.18M 7,859,529 shares | 0.03% | +50.63K(+0.6%)Added | SEC filing ↗ Aug 13, 2026 | ▾ |
| 05 | WELLINGTON MANAGEMENT GROUP LLP CIK 902219 · View history | $606.68M 7,651,415 shares | 0.10% | +1.26M(+19.7%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 06 | VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · View history | $571.80M 7,211,497 shares | 0.01% | +93.17K(+1.3%)Added | SEC filing ↗ Aug 13, 2026 | ▾ |
| 07 | TWO SIGMA INVESTMENTS, LP CIK 1179392 · View history | $495.75M 6,252,342 shares | 0.37% | +394.71K(+6.7%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 08 | ROYAL BANK OF CANADA CIK 1000275 · View history | $490.21M 6,182,479 shares | 0.08% | +2.38M(+62.6%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 09 | STATE STREET CORP CIK 93751 · View history | $343.71M 4,334,848 shares | 0.01% | +339.28K(+8.5%)Added | SEC filing ↗ Aug 7, 2026 | ▾ |
| 10 | T. Rowe Price Investment Management, Inc. CIK 1897612 · View history | $313.94M 3,959,372 shares | 0.21% | -2.20M(-35.7%)Reduced | SEC filing ↗ Aug 14, 2026 | ▾ |
| 11 | GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history | $294.75M 3,584,024 shares | 0.02% | -400.31K(-10.0%)Reduced | SEC filing ↗ Aug 12, 2026 | ▾ |
| 12 | PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history | $252.50M 3,184,500 shares | 0.03% | +159.25K(+5.3%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 13 | Artisan Partners Limited Partnership CIK 1466153 · View history | $209.33M 2,640,024 shares | 0.34% | +581.72K(+28.3%)Added | SEC filing ↗ Aug 13, 2026 | ▾ |
| 14 | Tweedy, Browne Co LLC CIK 732905 · View history | $180.81M 2,280,311 shares | 13.70% | +4.69K(+0.2%)Added | SEC filing ↗ Aug 7, 2026 | ▾ |
| 15 | Deep Track Capital, LP CIK 1856083 · View history | $174.44M 2,200,000 shares | 2.57% | +250.00K(+12.8%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 16 | GOLDMAN SACHS GROUP INC CIK 886982 · View history | $167.30M 2,109,945 shares | 0.02% | +410.10K(+24.1%)Added | SEC filing ↗ Aug 14, 2026 | ▾ |
| 17 | BAKER BROS. ADVISORS LP CIK 1263508 · View history | $162.36M 2,047,727 shares | 0.81% | 0(0.0%)Unchanged | SEC filing ↗ Aug 14, 2026 | ▾ |
| 18 | DEERFIELD MANAGEMENT COMPANY, L.P. CIK 1009258 · View history | $156.97M 1,979,669 shares | 1.64% | 0(0.0%)Unchanged | SEC filing ↗ Aug 14, 2026 | ▾ |
| 19 | AMERICAN CENTURY COMPANIES INC CIK 748054 · View history | $154.38M 1,947,076 shares | 0.07% | +283.27K(+17.0%)Added | SEC filing ↗ Aug 12, 2026 | ▾ |
| 20 | FRANKLIN RESOURCES INC CIK 38777 · View history | $128.72M 1,623,377 shares | 0.03% | +48.35K(+3.1%)Added | SEC filing ↗ Aug 13, 2026 | ▾ |
Showing 20 / 505 institutions. The complete set is available through the API.
Coverage & totals by quarter
Reporting institutions by quarter
Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.
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