Company · Ownership research

LEXICON PHARMACEUTICALS, INC. LXRX

CIK 0001062822 · CUSIP 528872302

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 528872302 (LXRX), not CUSIP 528872902 (LXRX), CUSIP 528872952 (LXRX), and does not merge CUSIPs.

This page lists the top 20 of 128 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	Artal Group S.A. CIK 1053906 · View history	$62.64M 136,180,481 shares	7.08%	0(0.00%)Unchanged	SEC filing ↗ May 14, 2025	▾
02	Siren, L.L.C. CIK 2005245 · Amended · View history	$17.93M 38,918,903 shares	1.01%	0(0.00%)Unchanged	SEC filing ↗ May 23, 2025	▾
03	FMR LLC CIK 315066 · Amended · View history	$15.92M 34,543,197 shares	0.00%	-17.43M(-33.50%)Reduced	SEC filing ↗ Nov 5, 2026	▾
04	BlackRock, Inc. CIK 2012383 · View history	$4.61M 10,013,007 shares	0.00%	-320.15K(-3.10%)Reduced	SEC filing ↗ May 2, 2025	▾
05	VANGUARD GROUP INC CIK 102909 · View history	$4.41M 9,557,175 shares	0.00%	-324.55K(-3.30%)Reduced	SEC filing ↗ May 9, 2025	▾
06	Schonfeld Strategic Advisors LLC CIK 1665241 · View history	$3.78M 8,212,993 shares	0.03%	+654.37K(+8.70%)Added	SEC filing ↗ May 15, 2025	▾
07	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$1.70M 3,689,271 shares	0.00%	+168.02K(+4.80%)Added	SEC filing ↗ May 13, 2025	▾
08	STATE STREET CORP CIK 93751 · View history	$1.20M 2,607,574 shares	0.00%	-110.67K(-4.10%)Reduced	SEC filing ↗ May 15, 2025	▾
09	CIBC Private Wealth Group LLC CIK 1298088 · View history	$1.12M 2,240,000 shares	0.00%	+2.24MNew	SEC filing ↗ May 14, 2025	▾
10	UBS Group AG CIK 1610520 · View history	$965.95K 2,095,340 shares	0.00%	+1.41M(+205.40%)Added	SEC filing ↗ May 13, 2025	▾
11	Ikarian Capital, LLC CIK 1778253 · View history	$653.39K 1,417,952 shares	0.21%	-132.05K(-8.50%)Reduced	SEC filing ↗ May 15, 2025	▾
12	AQR CAPITAL MANAGEMENT LLC CIK 1167557 · View history	$540.62K 1,173,225 shares	0.00%	+1.17MNew	SEC filing ↗ May 15, 2025	▾
13	CHARLES SCHWAB INVESTMENT MANAGEMENT INC CIK 884546 · Amended · View history	$530.27K 1,150,771 shares	0.00%	-40.32K(-3.40%)Reduced	SEC filing ↗ Sep 15, 2025	▾
14	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$530.04K 1,150,268 shares	0.03%	+300.00K(+35.30%)Added	SEC filing ↗ May 15, 2025	▾
15	NORTHERN TRUST CORP CIK 73124 · View history	$511.44K 1,109,887 shares	0.00%	-198.76K(-15.20%)Reduced	SEC filing ↗ May 13, 2025	▾
16	SUSQUEHANNA INTERNATIONAL GROUP, LLP CIK 1446194 · View history	$438.28K 951,135 shares	0.00%	+400.24K(+72.70%)Added	SEC filing ↗ May 14, 2025	▾
17	Hennion & Walsh Asset Management, Inc. CIK 1861642 · View history	$382.49K 830,054 shares	0.02%	-33.20K(-3.80%)Reduced	SEC filing ↗ Apr 10, 2025	▾
18	GSA CAPITAL PARTNERS LLP CIK 1362033 · View history	$372.00K 807,492 shares	0.03%	+807.49KNew	SEC filing ↗ May 8, 2025	▾
19	Monaco Asset Management SAM CIK 1803593 · View history	$338.30K 734,148 shares	0.17%	+734.15KNew	SEC filing ↗ May 8, 2025	▾
20	MORGAN STANLEY CIK 895421 · View history	$295.66K 641,629 shares	0.00%	+115.48K(+21.90%)Added	SEC filing ↗ May 15, 2025	▾

Showing 20 / 128 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

128

Cancelled or null records excluded

Disclosed shares

265,779,098

Not deduplicated across managers

Disclosed value

$122.47M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

LEXICON PHARMACEUTICALS, INC. · Q1 2025

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.