Company · Ownership research

Praxis Precision Medicines, Inc. PRAX

CIK 0001689548 · CUSIP 74006W207

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 74006W207 (PRAX), not CUSIP 74006W907 (PRAX), CUSIP 74006W957 (PRAX), CUSIP 74006W108 (PRAX), CUSIP SBNGFSD88 (PRAX), and does not merge CUSIPs.

This page lists the top 20 of 152 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	JANUS HENDERSON GROUP PLC CIK 1274173 · View history	$146.48M 2,763,859 shares	0.07%	+230.45K(+9.10%)Added	SEC filing ↗ Nov 14, 2025	▾
02	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$125.83M 2,374,085 shares	0.20%	+399.50K(+20.20%)Added	SEC filing ↗ Nov 14, 2025	▾
03	BlackRock, Inc. CIK 2012383 · View history	$95.46M 1,801,080 shares	0.00%	+210.95K(+13.30%)Added	SEC filing ↗ Nov 12, 2025	▾
04	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$82.92M 1,564,554 shares	2.40%	+811.63K(+107.80%)Added	SEC filing ↗ Nov 14, 2025	▾
05	Point72 Asset Management, L.P. CIK 1603466 · View history	$79.29M 1,495,986 shares	0.17%	+541.91K(+56.80%)Added	SEC filing ↗ Nov 14, 2025	▾
06	VANGUARD GROUP INC CIK 102909 · View history	$67.17M 1,267,286 shares	0.00%	+51.64K(+4.20%)Added	SEC filing ↗ Nov 7, 2025	▾
07	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$53.19M 1,003,490 shares	0.01%	-469.58K(-31.90%)Reduced	SEC filing ↗ Nov 14, 2025	▾
08	Cormorant Asset Management, LP CIK 1583977 · View history	$53.00M 1,000,000 shares	3.66%	-625.00K(-38.50%)Reduced	SEC filing ↗ Nov 14, 2025	▾
09	STATE STREET CORP CIK 93751 · View history	$48.08M 907,108 shares	0.00%	+209.01K(+29.90%)Added	SEC filing ↗ Nov 14, 2025	▾
10	Soleus Capital Management, L.P. CIK 1802630 · View history	$45.54M 859,166 shares	2.43%	-107.57K(-11.10%)Reduced	SEC filing ↗ Nov 14, 2025	▾
11	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) CIK 1009258 · View history	$44.57M 840,851 shares	0.68%	+153.92K(+22.40%)Added	SEC filing ↗ Nov 14, 2025	▾
12	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$36.54M 689,488 shares	0.26%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2025	▾
13	MORGAN STANLEY CIK 895421 · Amended · View history	$34.11M 643,495 shares	0.00%	-582.84K(-47.50%)Reduced	SEC filing ↗ May 27, 2026	▾
14	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$31.43M 593,021 shares	0.00%	+367.03K(+162.40%)Added	SEC filing ↗ Nov 14, 2025	▾
15	Driehaus Capital Management LLC CIK 938206 · View history	$26.53M 500,551 shares	0.19%	-30.44K(-5.70%)Reduced	SEC filing ↗ Nov 14, 2025	▾
16	BANK OF AMERICA CORP /DE/ CIK 70858 · Amended · View history	$25.59M 482,861 shares	0.00%	+29.46K(+6.50%)Added	SEC filing ↗ Feb 3, 2026	▾
17	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$24.23M 457,032 shares	0.00%	+5.30K(+1.20%)Added	SEC filing ↗ Nov 12, 2025	▾
18	Woodline Partners LP CIK 1784547 · View history	$22.14M 417,669 shares	0.10%	+371.72K(+808.90%)Added	SEC filing ↗ Nov 14, 2025	▾
19	Assenagon Asset Management S.A. CIK 1546007 · View history	$21.72M 409,779 shares	0.03%	-194.52K(-32.20%)Reduced	SEC filing ↗ Oct 7, 2025	▾
20	CIBC Asset Management Inc CIK 1021926 · View history	$20.60M 388,759 shares	0.06%	0(0.00%)Unchanged	SEC filing ↗ Oct 31, 2025	▾

Showing 20 / 152 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

152

Cancelled or null records excluded

Disclosed shares

24,666,148

Not deduplicated across managers

Disclosed value

$1.31B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Praxis Precision Medicines, Inc. · Q3 2025

Explore all 152 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.