Company · Ownership research

Prelude Therapeutics Inc PRLD

CIK 0001678660 · CUSIP 74065P101

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 74065P101 (PRLD), not CUSIP 74065P951 (PRLD), and does not merge CUSIPs.

This page lists the top 20 of 51 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	ORBIMED ADVISORS LLC CIK 1055951 · View history	$8.83M 10,909,256 shares	0.22%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
02	BAKER BROS. ADVISORS LP CIK 1263508 · View history	$8.19M 10,123,824 shares	0.08%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
03	VANGUARD GROUP INC CIK 102909 · View history	$754.45K 932,570 shares	0.00%	-76.63K(-7.60%)Reduced	SEC filing ↗ Aug 11, 2025	▾
04	PRICE T ROWE ASSOCIATES INC /MD/ CIK 80255 · View history	$743.00K 927,608 shares	0.00%	-48.54K(-5.00%)Reduced	SEC filing ↗ Aug 14, 2025	▾
05	RENAISSANCE TECHNOLOGIES LLC CIK 1037389 · View history	$470.91K 581,800 shares	0.00%	-74.90K(-11.40%)Reduced	SEC filing ↗ Aug 13, 2025	▾
06	ACADIAN ASSET MANAGEMENT LLC CIK 916542 · View history	$436.00K 540,565 shares	0.00%	+11.24K(+2.10%)Added	SEC filing ↗ Aug 7, 2025	▾
07	BlackRock, Inc. CIK 2012383 · View history	$350.11K 432,559 shares	0.00%	-615.17K(-58.70%)Reduced	SEC filing ↗ Aug 12, 2025	▾
08	MORGAN STANLEY CIK 895421 · View history	$230.18K 284,382 shares	0.00%	-18.40K(-6.10%)Reduced	SEC filing ↗ Aug 14, 2025	▾
09	MILLENNIUM MANAGEMENT LLC CIK 1273087 · View history	$201.07K 248,423 shares	0.00%	+101.65K(+69.30%)Added	SEC filing ↗ Aug 14, 2025	▾
10	TWO SIGMA ADVISERS, LP CIK 1478735 · View history	$182.12K 225,000 shares	0.00%	-35.40K(-13.60%)Reduced	SEC filing ↗ Aug 14, 2025	▾
11	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$176.13K 217,568 shares	0.00%	-187.39K(-46.30%)Reduced	SEC filing ↗ Aug 8, 2025	▾
12	CANTOR FITZGERALD, L. P. CIK 1024896 · View history	$171.48K 211,859 shares	0.00%	+211.86KNew	SEC filing ↗ Aug 14, 2025	▾
13	TD Asset Management Inc CIK 1056053 · View history	$130.03K 160,652 shares	0.00%	0(0.00%)Unchanged	SEC filing ↗ Jul 28, 2025	▾
14	TWO SIGMA INVESTMENTS, LP CIK 1179392 · View history	$125.44K 154,977 shares	0.00%	-28.69K(-15.60%)Reduced	SEC filing ↗ Aug 14, 2025	▾
15	GOLDMAN SACHS GROUP INC CIK 886982 · View history	$120.75K 149,178 shares	0.00%	-6.04K(-3.90%)Reduced	SEC filing ↗ Aug 14, 2025	▾
16	UBS Group AG CIK 1610520 · View history	$84.30K 104,204 shares	0.00%	+8.05K(+8.40%)Added	SEC filing ↗ Aug 14, 2025	▾
17	STATE STREET CORP CIK 93751 · View history	$78.99K 97,592 shares	0.00%	-188.45K(-65.90%)Reduced	SEC filing ↗ Aug 14, 2025	▾
18	JANE STREET GROUP, LLC CIK 1595888 · View history	$74.27K 91,753 shares	0.00%	+91.75KNew	SEC filing ↗ Aug 14, 2025	▾
19	BRIDGEWAY CAPITAL MANAGEMENT, LLC CIK 1107261 · View history	$71.63K 88,500 shares	0.00%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2025	▾
20	CHARLES SCHWAB INVESTMENT MANAGEMENT INC CIK 884546 · View history	$65.44K 80,845 shares	0.00%	-33.20K(-29.10%)Reduced	SEC filing ↗ Aug 12, 2025	▾

Showing 20 / 51 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

Cancelled or null records excluded

Disclosed shares

27,188,088

Not deduplicated across managers

Disclosed value

$22.00M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Prelude Therapeutics Inc · Q2 2025

Explore all 51 reporting institutions.

This page includes 20 of 51 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.