EcoR1 Capital, LLC
CIK 1587114 · Holdings on Jun 30, 2026 · First reported Aug 14, 2026
Top ten holdings
Q2 2026- ZYME29.77%
- ANAB26.37%
- AKTS7.71%
- CGON5.26%
- ETON3.90%
- CRSP3.76%
- ORIC3.61%
- TRAX3.17%
- LKFT2.48%
- NGNE1.98%
Share classes counted separately88.01%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- ANABWeight increased · +7.69 pp18.68% → 26.37%Shares 0 (0.00%)
- ZYMEWeight increased · +5.19 pp24.58% → 29.77%Shares 0 (0.00%)
- AKTSWeight increased · +4.02 pp3.69% → 7.71%Shares 0 (0.00%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 28
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | ZYMEZYMEWORKS INC View history and evidence | $600.45M | 29.77% | 22.97M shares | 24.58% → 29.77%+5.19 pp 0 (0.00%) | Unchanged | ▾ |
| 02 | ANABANAPTYSBIO INC View history and evidence | $531.91M | 26.37% | 7.88M shares | 18.68% → 26.37%+7.69 pp 0 (0.00%) | Unchanged | ▾ |
| 03 | AKTSAKTIS ONCOLOGY INC View history and evidence | $155.49M | 7.71% | 4.82M shares | 3.69% → 7.71%+4.02 pp 0 (0.00%) | Unchanged | ▾ |
| 04 | CGONCG ONCOLOGY INC View history and evidence | $106.17M | 5.26% | 1.49M shares | 3.19% → 5.26%+2.07 pp +392.30K (+35.60%) | Added | ▾ |
| 05 | ETONETON PHARMACEUTICALS INC View history and evidence | $78.62M | 3.90% | 2.17M shares | 2.29% → 3.90%+1.61 pp 0 (0.00%) | Unchanged | ▾ |
| 06 | CRSPCRISPR THERAPEUTICS AGNAMEN AKT View history and evidence | $75.77M | 3.76% | 1.39M shares | 2.82% → 3.76%+0.94 pp 0 (0.00%) | Unchanged | ▾ |
| 07 | ORICORIC PHARMACEUTICALS INC View history and evidence | $72.87M | 3.61% | 6.73M shares | 3.64% → 3.61%-0.03 pp 0 (0.00%) | Unchanged | ▾ |
| 08 | TRAXFIRST TRACKS BIOTHERAPEUTICSORD SHS ADDED View history and evidence | $63.87M | 3.17% | 3.17M shares | Prior unavailable +3.17M | New | ▾ |
| 09 | LKFTLAKEFRONT BIOTHERAPEUTIC-ADRSPON ADR View history and evidence | $49.98M | 2.48% | 1.67M shares | 2.14% → 2.48%+0.34 pp 0 (0.00%) | Unchanged | ▾ |
| 10 | NGNENEUROGENE INC View history and evidence | $39.98M | 1.98% | 1.27M shares | 1.10% → 1.98%+0.88 pp 0 (0.00%) | Unchanged | ▾ |
Options overlay 2
$39.98M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
CGONCG ONCOLOGY INC View history and evidence | Call | 561.50K | $39.89M | +561.50K | ▾ |
AARDAARDVARK THERAPEUTICS INC View history and evidence | Call | 14.70K | $84.67K | +14.70K | ▾ |
2 / 2 options · preview only
Exited positions 8
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| JAZZ JAZZ PHARMACEUTICALS PLC | Non-derivative | -1,706,469 | -$322.61M | SEC filing ↗ | SEC filing ↗ |
| CNTA CENTESSA PHARMACEUTICALS-ADR | Non-derivative | -6,000,000 | -$238.32M | SEC filing ↗ | SEC filing ↗ |
| CRNX CRINETICS PHARMACEUTICALS IN | Non-derivative | -4,288,120 | -$155.74M | SEC filing ↗ | SEC filing ↗ |
3 / 8 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1587114 · Period 2026-06-30
Data loaded 2026-09-23 · First reported 2026-08-14
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 2056733459
}Research all 33 reported holdings.
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