EcoR1 Capital, LLC
CIK 1587114 · Holdings on Mar 31, 2026 · First reported May 15, 2026
Top ten holdings
Q1 2026- ZYME24.58%
- ANAB18.68%
- JAZZ13.79%
- CNTA10.18%
- CRNX6.66%
- AKTS3.69%
- ORIC3.64%
- CGON3.19%
- CRSP2.82%
- ETON2.29%
Share classes counted separately89.52%
Portfolio value by quarter
What changed this quarter?
Within preview · weight change- CNTAWeight increased · +6.62 pp3.56% → 10.18%Shares +2.88M (+92.62%)
- ZYMEWeight decreased · -3.03 pp27.61% → 24.58%Shares 0 (0.00%)
- CRNXWeight decreased · -2.45 pp9.11% → 6.66%Shares 0 (0.00%)
Weight = security value ÷ total reported holdings value. Changes are in percentage points; price moves also affect weights, so they are not trade sizes.
Top 10 holdings 29
USD · B = billion · M = million; expand a row for exact values| # | Security | Value | Weight | Quantity | Weight / quantity change | Activity | |
|---|---|---|---|---|---|---|---|
| 01 | ZYMEZYMEWORKS INC View history and evidence | $575.18M | 24.58% | 22.97M shares | 27.61% → 24.58%-3.03 pp 0 (0.00%) | Unchanged | ↗▾ |
| 02 | ANABANAPTYSBIO INC View history and evidence | $437.03M | 18.68% | 7.88M shares | 17.44% → 18.68%+1.24 pp 0 (0.00%) | Unchanged | ↗▾ |
| 03 | JAZZJAZZ PHARMACEUTICALS PLCSHS USD View history and evidence | $322.61M | 13.79% | 1.71M shares | 13.24% → 13.79%+0.55 pp 0 (0.00%) | Unchanged | ↗▾ |
| 04 | CNTACENTESSA PHARMACEUTICALS-ADRSPONSORED ADS View history and evidence | $238.32M | 10.18% | 6.00M shares | 3.56% → 10.18%+6.62 pp +2.88M (+92.62%) | Added | ↗▾ |
| 05 | CRNXCRINETICS PHARMACEUTICALS IN View history and evidence | $155.74M | 6.66% | 4.29M shares | 9.11% → 6.66%-2.45 pp 0 (0.00%) | Unchanged | ↗▾ |
| 06 | AKTSAKTIS ONCOLOGY INCCOM ADDED View history and evidence | $86.31M | 3.69% | 4.82M shares | Prior unavailable +4.82M | New | ↗▾ |
| 07 | ORICORIC PHARMACEUTICALS INC View history and evidence | $85.25M | 3.64% | 6.73M shares | 2.51% → 3.64%+1.13 pp 0 (0.00%) | Unchanged | ↗▾ |
| 08 | CGONCG ONCOLOGY INC View history and evidence | $74.58M | 3.19% | 1.10M shares | 1.46% → 3.19%+1.73 pp +330.00K (+42.75%) | Added | ↗▾ |
| 09 | CRSPCRISPR THERAPEUTICS AGNAMEN AKT View history and evidence | $66.09M | 2.82% | 1.39M shares | 3.33% → 2.82%-0.51 pp 0 (0.00%) | Unchanged | ↗▾ |
| 10 | ETONETON PHARMACEUTICALS INC View history and evidence | $53.60M | 2.29% | 2.17M shares | 1.57% → 2.29%+0.72 pp +141.39K (+6.96%) | Added | ↗▾ |
Options overlay 1
$16.32M notionalPut and Call positions are separate. Notional is based on underlying securities, not option premium, market value or net exposure. Quantities are underlying shares.
| Security | Put / Call | Underlying shares | Notional | Quantity change | |
|---|---|---|---|---|---|
CNTACENTESSA PHARMACEUTICALS-ADRSPONSORED ADS View history and evidence | Call | 410.80K | $16.32M | +410.80K | ▾ |
1 / 1 options · preview only
Exited positions 11
| Security | Type | Shares out | Value out | Previous filing | This filing |
|---|---|---|---|---|---|
| IMNM IMMUNOME INC | Non-derivative | -2,855,590 | -$61.34M | SEC filing ↗ | SEC filing ↗ |
| GPCR STRUCTURE THERAPEUTICS INC | Non-derivative | -334,380 | -$23.26M | SEC filing ↗ | SEC filing ↗ |
| PCVX VAXCYTE INC | Non-derivative | -450,000 | -$20.76M | SEC filing ↗ | SEC filing ↗ |
3 / 11 preview exits. Up to 30 exit records are previewed. Exit means absent from the current filing; execution date, price and proceeds are unknown.
Every number has a source.
CIK 1587114 · Period 2026-03-31
Data loaded 2026-09-23 · First reported 2026-05-15
Amendments and versions
{
"amendments_merged": null,
"prior_versions": null,
"cover_table_value": 2356318840
}Take these holdings further.
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