Company · Ownership research

Zymeworks Inc. ZYME

CIK 0001937653 · CUSIP 98985Y108

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 98985Y108 (ZYME), not CUSIP 98985Y908 (ZYME), CUSIP 98985Y958 (ZYME), CUSIP 98985W102 (ZYME), and does not merge CUSIPs.

This page lists the top 20 of 164 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$168.64M 13,437,473 shares	5.78%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2024	▾
02	MORGAN STANLEY CIK 895421 · Amended · View history	$64.09M 5,106,869 shares	0.00%	+867.42K(+20.50%)Added	SEC filing ↗ May 14, 2025	▾
03	Redmile Group, LLC CIK 1425738 · View history	$64.03M 5,101,911 shares	3.77%	-109.13K(-2.10%)Reduced	SEC filing ↗ Nov 14, 2024	▾
04	BVF INC/IL CIK 1056807 · View history	$57.83M 4,607,935 shares	1.69%	-1.26M(-21.50%)Reduced	SEC filing ↗ Nov 14, 2024	▾
05	BlackRock, Inc. CIK 2012383 · View history	$53.51M 4,263,595 shares	0.00%	—	SEC filing ↗ Nov 13, 2024	▾
06	Rubric Capital Management LP CIK 1687509 · View history	$49.16M 3,917,331 shares	0.80%	0(0.00%)Unchanged	SEC filing ↗ Nov 13, 2024	▾
07	VANGUARD GROUP INC CIK 102909 · View history	$35.87M 2,858,514 shares	0.00%	+161.14K(+6.00%)Added	SEC filing ↗ Nov 13, 2024	▾
08	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$27.36M 2,180,020 shares	0.59%	+512.31K(+30.70%)Added	SEC filing ↗ Nov 14, 2024	▾
09	BNP PARIBAS ASSET MANAGEMENT Holding S.A. CIK 1520354 · View history	$24.42M 1,945,491 shares	0.06%	+14.60K(+0.80%)Added	SEC filing ↗ Nov 8, 2024	▾
10	DEUTSCHE BANK AG\ CIK 948046 · Amended · View history	$19.19M 1,528,923 shares	0.01%	-829.27K(-35.20%)Reduced	SEC filing ↗ Jun 26, 2025	▾
11	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC CIK 861177 · View history	$19.13M 1,524,084 shares	0.00%	-378.32K(-19.90%)Reduced	SEC filing ↗ Nov 14, 2024	▾
12	FARALLON CAPITAL MANAGEMENT LLC CIK 909661 · Amended · View history	$17.08M 1,361,000 shares	0.09%	-240.00K(-15.00%)Reduced	SEC filing ↗ Nov 14, 2024	▾
13	STATE STREET CORP CIK 93751 · View history	$14.71M 1,171,777 shares	0.00%	+67.40K(+6.10%)Added	SEC filing ↗ Nov 14, 2024	▾
14	Nextech Invest Ltd. CIK 1911010 · View history	$13.98M 1,113,946 shares	1.96%	+1.11MNew	SEC filing ↗ Nov 14, 2024	▾
15	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$13.80M 1,100,000 shares	0.99%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2024	▾
16	Samsara BioCapital, LLC CIK 1744967 · View history	$12.55M 1,000,000 shares	2.41%	0(0.00%)Unchanged	SEC filing ↗ Nov 14, 2024	▾
17	Prosight Management, LP CIK 1617201 · View history	$11.52M 917,599 shares	2.92%	-262.40K(-22.20%)Reduced	SEC filing ↗ Nov 14, 2024	▾
18	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$10.66M 849,502 shares	0.00%	+133.87K(+18.70%)Added	SEC filing ↗ Nov 7, 2024	▾
19	BRIDGEWAY CAPITAL MANAGEMENT, LLC CIK 1107261 · View history	$9.32M 742,561 shares	0.20%	+17.02K(+2.30%)Added	SEC filing ↗ Nov 14, 2024	▾
20	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$8.96M 713,915 shares	0.00%	+965(+0.10%)Added	SEC filing ↗ Nov 12, 2024	▾

Showing 20 / 164 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

164

Cancelled or null records excluded

Disclosed shares

66,577,293

Not deduplicated across managers

Disclosed value

$835.64M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Zymeworks Inc. · Q3 2024

Explore all 164 reporting institutions.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.