Company · Ownership research

Zymeworks Inc. ZYME

CIK 0001937653 · CUSIP 98985Y108

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 98985Y108 (ZYME), not CUSIP 98985Y908 (ZYME), CUSIP 98985Y958 (ZYME), CUSIP 98985W102 (ZYME), and does not merge CUSIPs.

This page lists the top 20 of 202 rows by value; the complete set is available through the API.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$600.45M 22,970,388 shares	29.77%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾
02	Rubric Capital Management LP CIK 1687509 · View history	$182.98M 7,000,000 shares	1.68%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾
03	BlackRock, Inc. CIK 2012383 · View history	$111.12M 4,251,030 shares	0.00%	-302.86K(-6.70%)Reduced	SEC filing ↗ Aug 7, 2026	▾
04	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$109.34M 4,182,953 shares	1.70%	+672.88K(+19.20%)Added	SEC filing ↗ Aug 14, 2026	▾
05	BVF INC/IL CIK 1056807 · View history	$95.39M 3,649,142 shares	2.44%	-85.00K(-2.30%)Reduced	SEC filing ↗ Aug 14, 2026	▾
06	MORGAN STANLEY CIK 895421 · View history	$58.33M 2,231,260 shares	0.00%	-249.31K(-10.10%)Reduced	SEC filing ↗ Aug 13, 2026	▾
07	BNP PARIBAS ASSET MANAGEMENT Holding S.A. CIK 1520354 · View history	$46.56M 1,781,116 shares	0.05%	-126.92K(-6.70%)Reduced	SEC filing ↗ Aug 13, 2026	▾
08	VANGUARD CAPITAL MANAGEMENT LLC CIK 2100119 · View history	$40.75M 1,558,998 shares	0.00%	-146.58K(-8.60%)Reduced	SEC filing ↗ Aug 13, 2026	▾
09	Assenagon Asset Management S.A. CIK 1546007 · Amended · View history	$32.73M 1,252,027 shares	0.04%	+524.04K(+72.00%)Added	SEC filing ↗ Aug 21, 2026	▾
10	Nextech Invest, Ltd. CIK 1595430 · View history	$29.12M 1,113,946 shares	1.38%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾
11	STATE STREET CORP CIK 93751 · View history	$28.45M 1,088,216 shares	0.00%	+76.44K(+7.60%)Added	SEC filing ↗ Aug 7, 2026	▾
12	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$26.00M 994,955 shares	0.00%	-144.18K(-12.70%)Reduced	SEC filing ↗ Aug 11, 2026	▾
13	CITADEL ADVISORS LLC CIK 1423053 · Amended · View history	$23.90M 914,136 shares	0.01%	-235.88K(-20.50%)Reduced	SEC filing ↗ Sep 2, 2026	▾
14	NOMURA ASSET MANAGEMENT INTERNATIONAL INC. CIK 921739 · View history	$23.26M 889,802 shares	0.03%	+889.80KNew	SEC filing ↗ Aug 14, 2026	▾
15	FMR LLC CIK 315066 · View history	$18.37M 702,568 shares	0.00%	+35.41K(+5.30%)Added	SEC filing ↗ Aug 13, 2026	▾
16	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$18.10M 692,410 shares	0.00%	+32.47K(+4.90%)Added	SEC filing ↗ Aug 12, 2026	▾
17	Prosight Management, LP CIK 1617201 · View history	$17.63M 674,434 shares	3.04%	+135.38K(+25.10%)Added	SEC filing ↗ Aug 14, 2026	▾
18	Qube Research & Technologies Ltd CIK 1729829 · View history	$15.52M 593,590 shares	0.02%	+81.65K(+15.90%)Added	SEC filing ↗ Aug 14, 2026	▾
19	VANGUARD PORTFOLIO MANAGEMENT LLC CIK 2100121 · View history	$13.33M 510,032 shares	0.00%	+10.16K(+2.00%)Added	SEC filing ↗ Aug 13, 2026	▾
20	Redmile Group, LLC CIK 1425738 · View history	$12.85M 491,654 shares	0.86%	0(0.00%)Unchanged	SEC filing ↗ Aug 14, 2026	▾

Showing 20 / 202 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

202

Cancelled or null records excluded

Disclosed shares

68,361,825

Not deduplicated across managers

Disclosed value

$1.79B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Zymeworks Inc. · Q2 2026

Explore all 202 reporting institutions.

This page includes 20 of 202 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.