Company · Ownership research

Zymeworks Inc. ZYME

CIK 0001937653 · CUSIP 98985Y108

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 98985Y108 (ZYME), not CUSIP 98985Y908 (ZYME), CUSIP 98985Y958 (ZYME), CUSIP 98985W102 (ZYME), and does not merge CUSIPs.

This page lists the top 20 of 186 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$205.56M 17,259,548 shares	12.21%	+2.23M(+14.80%)Added	SEC filing ↗ May 15, 2025	▾
02	Redmile Group, LLC CIK 1425738 · View history	$57.04M 4,788,945 shares	5.39%	-51.52K(-1.10%)Reduced	SEC filing ↗ May 15, 2025	▾
03	Rubric Capital Management LP CIK 1687509 · View history	$51.67M 4,338,444 shares	0.93%	+421.11K(+10.70%)Added	SEC filing ↗ May 14, 2025	▾
04	BVF INC/IL CIK 1056807 · View history	$51.32M 4,308,935 shares	2.09%	0(0.00%)Unchanged	SEC filing ↗ May 15, 2025	▾
05	BlackRock, Inc. CIK 2012383 · View history	$48.71M 4,089,421 shares	0.00%	-95.53K(-2.30%)Reduced	SEC filing ↗ May 2, 2025	▾
06	MORGAN STANLEY CIK 895421 · View history	$48.51M 4,073,463 shares	0.00%	-127.97K(-3.00%)Reduced	SEC filing ↗ May 15, 2025	▾
07	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC CIK 861177 · View history	$46.21M 3,879,945 shares	0.01%	+2.51M(+184.20%)Added	SEC filing ↗ May 19, 2025	▾
08	BNP PARIBAS ASSET MANAGEMENT Holding S.A. CIK 1520354 · View history	$26.18M 2,197,879 shares	0.07%	+60.23K(+2.80%)Added	SEC filing ↗ May 14, 2025	▾
09	PERCEPTIVE ADVISORS LLC CIK 1224962 · Amended · View history	$22.21M 1,864,672 shares	0.79%	-265.35K(-12.50%)Reduced	SEC filing ↗ Aug 6, 2025	▾
10	VANGUARD GROUP INC CIK 102909 · View history	$21.05M 1,767,041 shares	0.00%	-726.25K(-29.10%)Reduced	SEC filing ↗ May 9, 2025	▾
11	DEUTSCHE BANK AG\ CIK 948046 · View history	$18.49M 1,552,612 shares	0.01%	+5.84K(+0.40%)Added	SEC filing ↗ May 9, 2025	▾
12	Blackstone Inc. CIK 1393818 · View history	$16.47M 1,382,587 shares	0.07%	+812.87K(+142.70%)Added	SEC filing ↗ May 15, 2025	▾
13	Nextech Invest, Ltd. CIK 1595430 · View history	$13.27M 1,113,946 shares	3.08%	—	SEC filing ↗ May 15, 2025	▾
14	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$13.10M 1,100,000 shares	0.72%	0(0.00%)Unchanged	SEC filing ↗ May 15, 2025	▾
15	STATE STREET CORP CIK 93751 · View history	$12.92M 1,085,133 shares	0.00%	+172(0.00%)Added	SEC filing ↗ May 15, 2025	▾
16	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$12.86M 1,079,458 shares	0.00%	+106.72K(+11.00%)Added	SEC filing ↗ May 13, 2025	▾
17	Prosight Management, LP CIK 1617201 · View history	$11.40M 957,229 shares	3.75%	+137.23K(+16.70%)Added	SEC filing ↗ May 15, 2025	▾
18	BRIDGEWAY CAPITAL MANAGEMENT, LLC CIK 1107261 · View history	$9.13M 766,944 shares	0.23%	+7.29K(+1.00%)Added	SEC filing ↗ May 15, 2025	▾
19	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$8.40M 705,035 shares	0.00%	+15.15K(+2.20%)Added	SEC filing ↗ May 13, 2025	▾
20	Samsara BioCapital, LLC CIK 1744967 · View history	$7.94M 666,667 shares	1.42%	-333.33K(-33.30%)Reduced	SEC filing ↗ May 15, 2025	▾

Showing 20 / 186 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

186

Cancelled or null records excluded

Disclosed shares

70,591,163

Not deduplicated across managers

Disclosed value

$840.90M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Zymeworks Inc. · Q1 2025

Explore all 186 reporting institutions.

This page includes 20 of 186 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.