Company · Ownership research

Zymeworks Inc. ZYME

CIK 0001937653 · CUSIP 98985Y108

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 98985Y108 (ZYME), not CUSIP 98985Y908 (ZYME), CUSIP 98985Y958 (ZYME), CUSIP 98985W102 (ZYME), and does not merge CUSIPs.

This page lists the top 20 of 209 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$604.81M 22,970,388 shares	27.61%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
02	Rubric Capital Management LP CIK 1687509 · View history	$151.40M 5,750,000 shares	1.81%	+1.04M(+22.10%)Added	SEC filing ↗ Feb 13, 2026	▾
03	BlackRock, Inc. CIK 2012383 · View history	$121.00M 4,595,548 shares	0.00%	+606.01K(+15.20%)Added	SEC filing ↗ Feb 12, 2026	▾
04	BVF INC/IL CIK 1056807 · View history	$103.70M 3,938,641 shares	3.49%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
05	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$85.88M 3,261,850 shares	1.57%	+1.17M(+56.00%)Added	SEC filing ↗ Feb 17, 2026	▾
06	MORGAN STANLEY CIK 895421 · Amended · View history	$68.28M 2,593,080 shares	0.00%	-1.39M(-34.90%)Reduced	SEC filing ↗ May 27, 2026	▾
07	VANGUARD GROUP INC CIK 102909 · View history	$61.32M 2,328,727 shares	0.00%	+174.29K(+8.10%)Added	SEC filing ↗ Jan 29, 2026	▾
08	BNP PARIBAS ASSET MANAGEMENT Holding S.A. CIK 1520354 · View history	$47.98M 1,822,048 shares	0.06%	+1.82MNew	SEC filing ↗ Feb 13, 2026	▾
09	Siren, L.L.C. CIK 2005245 · View history	$44.24M 1,680,121 shares	1.32%	+1.68MNew	SEC filing ↗ Feb 13, 2026	▾
10	DEUTSCHE BANK AG\ CIK 948046 · View history	$42.02M 1,595,833 shares	0.01%	+50.94K(+3.30%)Added	SEC filing ↗ Feb 11, 2026	▾
11	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$30.52M 1,159,215 shares	0.01%	-31.62K(-2.70%)Reduced	SEC filing ↗ Feb 12, 2026	▾
12	Nextech Invest, Ltd. CIK 1595430 · View history	$29.33M 1,113,946 shares	2.84%	0(0.00%)Unchanged	SEC filing ↗ Feb 17, 2026	▾
13	STATE STREET CORP CIK 93751 · View history	$27.32M 1,037,642 shares	0.00%	-43.55K(-4.00%)Reduced	SEC filing ↗ Feb 13, 2026	▾
14	Capricorn Fund Managers Ltd CIK 1901361 · View history	$26.93M 1,022,840 shares	6.49%	+1.02MNew	SEC filing ↗ Jan 21, 2026	▾
15	Vestal Point Capital, LP CIK 1974915 · View history	$22.78M 865,000 shares	0.84%	-900.00K(-51.00%)Reduced	SEC filing ↗ Feb 17, 2026	▾
16	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP CIK 1164508 · View history	$18.43M 700,002 shares	0.01%	+386.25K(+123.10%)Added	SEC filing ↗ Feb 13, 2026	▾
17	ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 1165408 · View history	$17.47M 663,546 shares	0.03%	+99.55K(+17.70%)Added	SEC filing ↗ Feb 17, 2026	▾
18	Nuveen, LLC CIK 1871926 · View history	$17.07M 648,326 shares	0.00%	+82.94K(+14.70%)Added	SEC filing ↗ Feb 12, 2026	▾
19	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$17.06M 647,970 shares	0.00%	-30.67K(-4.50%)Reduced	SEC filing ↗ Feb 9, 2026	▾
20	Assenagon Asset Management S.A. CIK 1546007 · View history	$17.05M 647,374 shares	0.03%	-679.40K(-51.20%)Reduced	SEC filing ↗ Jan 9, 2026	▾

Showing 20 / 209 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

209

Cancelled or null records excluded

Disclosed shares

71,465,067

Not deduplicated across managers

Disclosed value

$1.88B

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Zymeworks Inc. · Q4 2025

Explore all 209 reporting institutions.

This page includes 20 of 209 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

Download CSV
Earlier quarters
Advanced screening & filtering
API & AI access

Already have an account?

＋ New accounts get free API credits to explore data beyond ownership filings.

For AI agents & developers

The initial HTML of this page carries its exact data as script#research-data (JSON): values, units, scope, preview limits and SEC sources. Read it directly, no script or API key needed; script#research-access says what needs an account. This page lists 20 of 209 reporting institutions; totals use the complete disclosed data.

Without an account: the last 3 years, with the row caps stated on the page. A free account opens all history on file on these pages and the CSV of what a page shows. Rows beyond the caps and bulk retrieval go through the authenticated API / MCP / CLI.

MCP  https://api.akkrudata.ai/mcp

akkru_institutional_holdings
{"action":"holders","cusip":"98985Y108","quarter":"2025Q4","type":"positions","page_size":100}

Connect to MCP with OAuth and follow the returned pagination. Credits and usage limits depend on the account.

MCP endpoint: https://api.akkrudata.ai/mcp
API / MCP / CLI documentation: /documents
llms.txt: /llms.txt

Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.