Company · Ownership research

Zymeworks Inc. ZYME

CIK 0001937653 · CUSIP 98985Y108

Insider trading Initial holdings Institutional holders

Quarter-end disclosures, not live holdings.

Several CUSIPs are reported for this company; this page shows CUSIP 98985Y108 (ZYME), not CUSIP 98985Y908 (ZYME), CUSIP 98985Y958 (ZYME), CUSIP 98985W102 (ZYME), and does not merge CUSIPs.

This page lists the top 20 of 174 rows by value; the complete set is available through the API.

Some filings reported values in thousands; those figures were scaled ×1,000 to dollars.

Top 20 institutions

Weight means this stock's share of the manager's own portfolio.

By reported value

#	Manager	Value	Manager weight	Change vs prior	Source
01	EcoR1 Capital, LLC CIK 1587114 · View history	$220.01M 15,028,079 shares	8.79%	+1.59M(+11.80%)Added	SEC filing ↗ Feb 14, 2025	▾
02	Redmile Group, LLC CIK 1425738 · View history	$70.86M 4,840,463 shares	4.94%	-261.45K(-5.10%)Reduced	SEC filing ↗ Feb 14, 2025	▾
03	BVF INC/IL CIK 1056807 · View history	$63.08M 4,308,935 shares	2.14%	-299.00K(-6.50%)Reduced	SEC filing ↗ Feb 14, 2025	▾
04	MORGAN STANLEY CIK 895421 · Amended · View history	$61.51M 4,201,437 shares	0.00%	-905.43K(-17.70%)Reduced	SEC filing ↗ May 15, 2025	▾
05	BlackRock, Inc. CIK 2012383 · View history	$61.27M 4,184,956 shares	0.00%	-78.64K(-1.80%)Reduced	SEC filing ↗ Feb 7, 2025	▾
06	Rubric Capital Management LP CIK 1687509 · View history	$57.35M 3,917,331 shares	1.04%	0(0.00%)Unchanged	SEC filing ↗ Feb 14, 2025	▾
07	VANGUARD GROUP INC CIK 102909 · View history	$36.50M 2,493,288 shares	0.00%	-365.23K(-12.80%)Reduced	SEC filing ↗ Feb 11, 2025	▾
08	BNP PARIBAS ASSET MANAGEMENT Holding S.A. CIK 1520354 · View history	$31.30M 2,137,653 shares	0.08%	+192.16K(+9.90%)Added	SEC filing ↗ Feb 12, 2025	▾
09	PERCEPTIVE ADVISORS LLC CIK 1224962 · View history	$31.18M 2,130,020 shares	0.87%	-50.00K(-2.30%)Reduced	SEC filing ↗ Feb 14, 2025	▾
10	DEUTSCHE BANK AG\ CIK 948046 · Amended · View history	$22.64M 1,546,772 shares	0.01%	+17.85K(+1.20%)Added	SEC filing ↗ Jun 30, 2025	▾
11	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC CIK 861177 · View history	$19.99M 1,365,111 shares	0.00%	-158.97K(-10.40%)Reduced	SEC filing ↗ Feb 14, 2025	▾
12	FARALLON CAPITAL MANAGEMENT LLC CIK 909661 · Amended · View history	$19.47M 1,329,974 shares	0.10%	-31.03K(-2.30%)Reduced	SEC filing ↗ Feb 14, 2025	▾
13	Nextech Invest Ltd. CIK 1911010 · View history	$16.31M 1,113,946 shares	2.65%	0(0.00%)Unchanged	SEC filing ↗ Feb 14, 2025	▾
14	TANG CAPITAL MANAGEMENT LLC CIK 1232621 · View history	$16.10M 1,100,000 shares	1.07%	0(0.00%)Unchanged	SEC filing ↗ Feb 14, 2025	▾
15	STATE STREET CORP CIK 93751 · View history	$15.88M 1,084,961 shares	0.00%	-86.82K(-7.40%)Reduced	SEC filing ↗ Feb 14, 2025	▾
16	Samsara BioCapital, LLC CIK 1744967 · View history	$14.64M 1,000,000 shares	2.01%	0(0.00%)Unchanged	SEC filing ↗ Feb 14, 2025	▾
17	DIMENSIONAL FUND ADVISORS LP CIK 354204 · View history	$14.24M 972,742 shares	0.00%	+123.24K(+14.50%)Added	SEC filing ↗ Feb 13, 2025	▾
18	Prosight Management, LP CIK 1617201 · View history	$12.00M 820,000 shares	3.36%	-97.60K(-10.60%)Reduced	SEC filing ↗ Feb 14, 2025	▾
19	BRIDGEWAY CAPITAL MANAGEMENT, LLC CIK 1107261 · View history	$11.12M 759,653 shares	0.25%	+17.09K(+2.30%)Added	SEC filing ↗ Feb 14, 2025	▾
20	GEODE CAPITAL MANAGEMENT, LLC CIK 1214717 · View history	$10.10M 689,884 shares	0.00%	-24.03K(-3.40%)Reduced	SEC filing ↗ Feb 12, 2025	▾

Showing 20 / 174 institutions. The complete set is available through the API.

Coverage & totals by quarter

Reporting institutions

174

Cancelled or null records excluded

Disclosed shares

66,481,117

Not deduplicated across managers

Disclosed value

$973.23M

Not market cap or free float

Reporting institutions by quarter

Counts also change with data coverage and reporting entities; they do not measure net buying. Distinct managers with a live stock row in this CUSIP; totals may include overlapping filings and are not a share of the company.

Zymeworks Inc. · Q4 2024

Explore all 174 reporting institutions.

This page includes 20 of 174 reporting institutions. Log in to look up the full history beyond 3 years, use advanced screening & filtering, download CSV, and get the complete set through the Akkru API.

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Sources, coverage & how to read this data

Figures are as reported to the SEC and merged with later amendments where Akkru could match them. Preview limits apply to what is listed, not to the totals, which come from the complete reported data. Nothing is zero-filled: a missing quarter or month is shown as missing.